Use KeyBinding to bind Key event to TextBox.InputBindings
<Window x:Class="Commands.NoCommandTextBox" xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation" xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml" Title="NoCommandTextBox" Height="300" Width="300"> <Grid> <TextBox Name="txt"/> </Grid> </Window> //File:Window.xaml.vb Imports System Imports System.Collections.Generic Imports System.Text Imports System.Windows Imports System.Windows.Controls Imports System.Windows.Data Imports System.Windows.Documents Imports System.Windows.Input Imports System.Windows.Media Imports System.Windows.Media.Imaging Imports System.Windows.Shapes Namespace Commands Public Partial Class NoCommandTextBox Inherits System.Windows.Window Public Sub New() InitializeComponent() txt.InputBindings.Add(New KeyBinding(ApplicationCommands.NotACommand, Key.C, ModifierKeys.Control)) End Sub Private Sub SuppressCommand(sender As Object, e As CanExecuteRoutedEventArgs) e.CanExecute = False e.Handled = True End Sub End Class End Namespace