de.bund.bfr.knime.pmm.common.XLSReader.java Source code

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/*******************************************************************************
 * Copyright (c) 2015 Federal Institute for Risk Assessment (BfR), Germany
 *
 * This program is free software: you can redistribute it and/or modify
 * it under the terms of the GNU General Public License as published by
 * the Free Software Foundation, either version 3 of the License, or
 * (at your option) any later version.
 *
 * This program is distributed in the hope that it will be useful,
 * but WITHOUT ANY WARRANTY; without even the implied warranty of
 * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
 * GNU General Public License for more details.
 *
 * You should have received a copy of the GNU General Public License
 * along with this program.  If not, see <http://www.gnu.org/licenses/>.
 *
 * Contributors:
 *     Department Biological Safety - BfR
 *******************************************************************************/
package de.bund.bfr.knime.pmm.common;

import java.io.File;
import java.io.FileInputStream;
import java.io.IOException;
import java.io.InputStream;
import java.net.URL;
import java.util.ArrayList;
import java.util.LinkedHashMap;
import java.util.LinkedHashSet;
import java.util.List;
import java.util.Map;
import java.util.Set;

import org.apache.poi.openxml4j.exceptions.InvalidFormatException;
import org.apache.poi.ss.usermodel.Cell;
import org.apache.poi.ss.usermodel.CellValue;
import org.apache.poi.ss.usermodel.FormulaEvaluator;
import org.apache.poi.ss.usermodel.Row;
import org.apache.poi.ss.usermodel.Sheet;
import org.apache.poi.ss.usermodel.Workbook;
import org.apache.poi.ss.usermodel.WorkbookFactory;

import com.google.common.collect.LinkedListMultimap;
import com.google.common.collect.ListMultimap;
import com.google.common.collect.Multimaps;

import de.bund.bfr.knime.pmm.common.generictablemodel.KnimeTuple;
import de.bund.bfr.knime.pmm.common.math.MathUtilities;
import de.bund.bfr.knime.pmm.common.pmmtablemodel.AttributeUtilities;
import de.bund.bfr.knime.pmm.common.pmmtablemodel.Model1Schema;
import de.bund.bfr.knime.pmm.common.pmmtablemodel.Model2Schema;
import de.bund.bfr.knime.pmm.common.pmmtablemodel.SchemaFactory;
import de.bund.bfr.knime.pmm.common.pmmtablemodel.TimeSeriesSchema;

public class XLSReader {

    public static String ID_COLUMN = "ID";
    public static String NAME_COLUMN = "Name";
    public static String CONCENTRATION_STDDEV_COLUMN = "Value StdDev";
    public static String CONCENTRATION_MEASURE_NUMBER = "Value Measurements";

    private List<String> warnings;
    private FormulaEvaluator evaluator;

    public XLSReader() {
        warnings = new ArrayList<>();
        evaluator = null;
    }

    public Map<String, KnimeTuple> getTimeSeriesTuples(File file, String sheet, Map<String, Object> columnMappings,
            String timeUnit, String concentrationUnit, String agentColumnName, Map<String, AgentXml> agentMappings,
            String matrixColumnName, Map<String, MatrixXml> matrixMappings, boolean preserveIds,
            List<Integer> usedIds) throws Exception {
        Workbook wb = getWorkbook(file);
        Sheet s = wb.getSheet(sheet);

        warnings.clear();
        evaluator = wb.getCreationHelper().createFormulaEvaluator();

        if (s == null) {
            throw new Exception("Sheet not found");
        }

        Map<String, KnimeTuple> tuples = new LinkedHashMap<>();
        Map<String, Integer> columns = getColumns(s);
        Map<String, Integer> miscColumns = new LinkedHashMap<>();
        Integer idColumn = null;
        Integer commentColumn = null;
        Integer timeColumn = null;
        Integer logcColumn = null;
        Integer stdDevColumn = null;
        Integer nMeasureColumn = null;
        Integer agentDetailsColumn = null;
        Integer matrixDetailsColumn = null;
        Integer agentColumn = null;
        Integer matrixColumn = null;
        String timeColumnName = null;
        String logcColumnName = null;
        String stdDevColumnName = null;
        String nMeasureColumnName = null;

        if (agentColumnName != null) {
            agentColumn = columns.get(agentColumnName);
        }

        if (matrixColumnName != null) {
            matrixColumn = columns.get(matrixColumnName);
        }

        for (String column : columns.keySet()) {
            if (columnMappings.containsKey(column)) {
                Object mapping = columnMappings.get(column);

                if (mapping instanceof MiscXml) {
                    miscColumns.put(column, columns.get(column));
                } else if (mapping.equals(ID_COLUMN)) {
                    idColumn = columns.get(column);
                } else if (mapping.equals(MdInfoXml.ATT_COMMENT)) {
                    commentColumn = columns.get(column);
                } else if (mapping.equals(AttributeUtilities.TIME)) {
                    timeColumn = columns.get(column);
                    timeColumnName = column;
                } else if (mapping.equals(AttributeUtilities.CONCENTRATION)) {
                    logcColumn = columns.get(column);
                    logcColumnName = column;
                } else if (mapping.equals(XLSReader.CONCENTRATION_STDDEV_COLUMN)) {
                    stdDevColumn = columns.get(column);
                    stdDevColumnName = column;
                } else if (mapping.equals(XLSReader.CONCENTRATION_MEASURE_NUMBER)) {
                    nMeasureColumn = columns.get(column);
                    nMeasureColumnName = column;
                } else if (mapping.equals(AttributeUtilities.AGENT_DETAILS)) {
                    agentDetailsColumn = columns.get(column);
                } else if (mapping.equals(AttributeUtilities.MATRIX_DETAILS)) {
                    matrixDetailsColumn = columns.get(column);
                }
            }
        }

        List<Integer> newIds = new ArrayList<>();
        ListMultimap<String, Row> rowsById = LinkedListMultimap.create();

        if (idColumn != null) {
            for (int i = 1; !isEndOfFile(s, i); i++) {
                Row row = s.getRow(i);
                Cell idCell = row.getCell(idColumn);

                if (hasData(idCell)) {
                    rowsById.put(getData(idCell), row);
                }
            }
        }

        for (Map.Entry<String, List<Row>> entry : Multimaps.asMap(rowsById).entrySet()) {
            KnimeTuple tuple = new KnimeTuple(SchemaFactory.createDataSchema());
            PmmXmlDoc timeSeriesXml = new PmmXmlDoc();
            String idString = entry.getKey();
            Row firstRow = entry.getValue().get(0);

            Cell commentCell = null;
            Cell agentDetailsCell = null;
            Cell matrixDetailsCell = null;
            Cell agentCell = null;
            Cell matrixCell = null;

            if (commentColumn != null) {
                commentCell = firstRow.getCell(commentColumn);
            }

            if (agentDetailsColumn != null) {
                agentDetailsCell = firstRow.getCell(agentDetailsColumn);
            }

            if (matrixDetailsColumn != null) {
                matrixDetailsCell = firstRow.getCell(matrixDetailsColumn);
            }

            if (agentColumn != null) {
                agentCell = firstRow.getCell(agentColumn);
            }

            if (matrixColumn != null) {
                matrixCell = firstRow.getCell(matrixColumn);
            }

            int id;

            if (preserveIds && !usedIds.isEmpty()) {
                id = usedIds.remove(0);
            } else {
                id = MathUtilities.getRandomNegativeInt();
            }

            newIds.add(id);
            tuple = new KnimeTuple(SchemaFactory.createDataSchema());
            tuple.setValue(TimeSeriesSchema.ATT_COMBASEID, idString);
            tuple.setValue(TimeSeriesSchema.ATT_CONDID, id);
            timeSeriesXml = new PmmXmlDoc();

            PmmXmlDoc dataInfo = new PmmXmlDoc();
            PmmXmlDoc agentXml = new PmmXmlDoc();
            PmmXmlDoc matrixXml = new PmmXmlDoc();

            if (commentCell != null) {
                dataInfo.add(new MdInfoXml(null, null, getData(commentCell), null, null));
            } else {
                dataInfo.add(new MdInfoXml(null, null, null, null, null));
            }

            if (hasData(agentCell) && agentMappings.get(getData(agentCell)) != null) {
                agentXml.add(agentMappings.get(getData(agentCell)));
            } else {
                agentXml.add(new AgentXml());
            }

            if (hasData(matrixCell) && matrixMappings.get(getData(matrixCell)) != null) {
                matrixXml.add(matrixMappings.get(getData(matrixCell)));
            } else {
                matrixXml.add(new MatrixXml());
            }

            if (hasData(agentDetailsCell)) {
                ((AgentXml) agentXml.get(0)).setDetail(getData(agentDetailsCell));
            }

            if (hasData(matrixDetailsCell)) {
                ((MatrixXml) matrixXml.get(0)).setDetail(getData(matrixDetailsCell));
            }

            tuple.setValue(TimeSeriesSchema.ATT_MDINFO, dataInfo);
            tuple.setValue(TimeSeriesSchema.ATT_AGENT, agentXml);
            tuple.setValue(TimeSeriesSchema.ATT_MATRIX, matrixXml);

            PmmXmlDoc miscXML = new PmmXmlDoc();

            for (String column : miscColumns.keySet()) {
                MiscXml misc = (MiscXml) columnMappings.get(column);
                Cell cell = firstRow.getCell(miscColumns.get(column));

                if (hasData(cell)) {
                    try {
                        misc.setValue(Double.parseDouble(getData(cell).replace(",", ".")));
                    } catch (NumberFormatException e) {
                        warnings.add(column + " value in row " + (firstRow.getRowNum() + 1) + " is not valid ("
                                + getData(cell) + ")");
                        misc.setValue(null);
                    }
                } else {
                    misc.setValue(null);
                }

                misc.setOrigUnit(misc.getUnit());
                miscXML.add(misc);
            }

            tuple.setValue(TimeSeriesSchema.ATT_MISC, miscXML);

            for (Row row : entry.getValue()) {
                Cell timeCell = null;
                Cell logcCell = null;
                Cell stdDevCell = null;
                Cell nMeasureCell = null;

                if (timeColumn != null) {
                    timeCell = row.getCell(timeColumn);
                }

                if (logcColumn != null) {
                    logcCell = row.getCell(logcColumn);
                }

                if (stdDevColumn != null) {
                    stdDevCell = row.getCell(stdDevColumn);
                }

                if (nMeasureColumn != null) {
                    nMeasureCell = row.getCell(nMeasureColumn);
                }

                Double time = null;
                Double logc = null;
                Double stdDev = null;
                Integer nMeasure = null;

                if (hasData(timeCell)) {
                    try {
                        time = Double.parseDouble(getData(timeCell).replace(",", "."));
                    } catch (NumberFormatException e) {
                        warnings.add(timeColumnName + " value in row " + (row.getRowNum() + 1) + " is not valid ("
                                + getData(timeCell) + ")");
                    }
                } else if (timeColumn != null) {
                    warnings.add(timeColumnName + " value in row " + (row.getRowNum() + 1) + " is missing");
                }

                if (hasData(logcCell)) {
                    try {
                        logc = Double.parseDouble(getData(logcCell).replace(",", "."));
                    } catch (NumberFormatException e) {
                        warnings.add(logcColumnName + " value in row " + (row.getRowNum() + 1) + " is not valid ("
                                + getData(logcCell) + ")");
                    }
                } else if (logcColumn != null) {
                    warnings.add(logcColumnName + " value in row " + (row.getRowNum() + 1) + " is missing");
                }

                if (hasData(stdDevCell)) {
                    try {
                        stdDev = Double.parseDouble(getData(stdDevCell).replace(",", "."));
                    } catch (NumberFormatException e) {
                        warnings.add(stdDevColumnName + " value in row " + (row.getRowNum() + 1) + " is not valid ("
                                + getData(stdDevCell) + ")");
                    }
                } else if (stdDevColumn != null) {
                    warnings.add(stdDevColumnName + " value in row " + (row.getRowNum() + 1) + " is missing");
                }

                if (hasData(nMeasureCell)) {
                    try {
                        String number = getData(nMeasureCell).replace(",", ".");

                        if (number.contains(".")) {
                            number = number.substring(0, number.indexOf("."));
                        }

                        nMeasure = Integer.parseInt(number);
                    } catch (NumberFormatException e) {
                        warnings.add(nMeasureColumnName + " value in row " + (row.getRowNum() + 1)
                                + " is not valid (" + getData(nMeasureCell) + ")");
                    }
                } else if (nMeasureColumn != null) {
                    warnings.add(nMeasureColumnName + " value in row " + (row.getRowNum() + 1) + " is missing");
                }

                for (String column : miscColumns.keySet()) {
                    PmmXmlDoc misc = tuple.getPmmXml(TimeSeriesSchema.ATT_MISC);
                    Cell cell = row.getCell(miscColumns.get(column));

                    if (hasData(cell)) {
                        try {
                            String param = ((MiscXml) columnMappings.get(column)).getName();
                            double value = Double.parseDouble(getData(cell).replace(",", "."));

                            if (!hasSameValue(param, value, misc)) {
                                warnings.add("Variable conditions cannot be imported: " + "Only first value for "
                                        + column + " is used");
                            }
                        } catch (NumberFormatException e) {
                        }
                    }
                }

                timeSeriesXml
                        .add(new TimeSeriesXml(null, time, timeUnit, logc, concentrationUnit, stdDev, nMeasure));
            }

            tuple.setValue(TimeSeriesSchema.ATT_TIMESERIES, timeSeriesXml);
            tuples.put(idString, tuple);
        }

        usedIds.clear();
        usedIds.addAll(newIds);

        return tuples;

    }

    public Map<String, KnimeTuple> getModelTuples(File file, String sheet, Map<String, Object> columnMappings,
            String agentColumnName, Map<String, AgentXml> agentMappings, String matrixColumnName,
            Map<String, MatrixXml> matrixMappings, KnimeTuple modelTuple, Map<String, String> modelMappings,
            Map<String, String> modelParamErrors, String modelDepMin, String modelDepMax, String modelDepUnit,
            String modelIndepMin, String modelIndepMax, String modelIndepUnit, String modelRmse, String modelR2,
            String modelAic, String modelDataPoints, Map<String, KnimeTuple> secModelTuples,
            Map<String, Map<String, String>> secModelMappings, Map<String, Map<String, String>> secModelParamErrors,
            Map<String, Map<String, String>> secModelIndepMins, Map<String, Map<String, String>> secModelIndepMaxs,
            Map<String, Map<String, String>> secModelIndepCategories,
            Map<String, Map<String, String>> secModelIndepUnits, Map<String, String> secModelRmse,
            Map<String, String> secModelR2, Map<String, String> secModelAic, Map<String, String> secModelDataPoints,
            boolean preserveIds, List<Integer> usedIds, Map<String, List<Integer>> secUsedIds,
            List<Integer> globalUsedIds) throws Exception {
        Workbook wb = getWorkbook(file);
        Sheet s = wb.getSheet(sheet);

        warnings.clear();
        evaluator = wb.getCreationHelper().createFormulaEvaluator();

        if (s == null) {
            throw new Exception("Sheet not found");
        }

        Map<String, KnimeTuple> tuples = new LinkedHashMap<>();
        Map<String, Integer> columns = getColumns(s);
        Map<String, Integer> miscColumns = new LinkedHashMap<>();
        Integer idColumn = null;
        Integer commentColumn = null;
        Integer agentDetailsColumn = null;
        Integer matrixDetailsColumn = null;
        Integer agentColumn = columns.get(agentColumnName);
        Integer matrixColumn = columns.get(matrixColumnName);
        Integer depMinColumn = columns.get(modelDepMin);
        Integer depMaxColumn = columns.get(modelDepMax);
        Integer indepMinColumn = columns.get(modelIndepMin);
        Integer indepMaxColumn = columns.get(modelIndepMax);
        Integer rmseColumn = columns.get(modelRmse);
        Integer r2Column = columns.get(modelR2);
        Integer aicColumn = columns.get(modelAic);
        Integer dataPointsColumn = columns.get(modelDataPoints);

        for (String column : columns.keySet()) {
            if (columnMappings.containsKey(column)) {
                Object mapping = columnMappings.get(column);

                if (mapping instanceof MiscXml) {
                    miscColumns.put(column, columns.get(column));
                } else if (mapping.equals(NAME_COLUMN)) {
                    idColumn = columns.get(column);
                } else if (mapping.equals(MdInfoXml.ATT_COMMENT)) {
                    commentColumn = columns.get(column);
                } else if (mapping.equals(AttributeUtilities.AGENT_DETAILS)) {
                    agentDetailsColumn = columns.get(column);
                } else if (mapping.equals(AttributeUtilities.MATRIX_DETAILS)) {
                    matrixDetailsColumn = columns.get(column);
                }
            }
        }

        int index = 0;
        List<Integer> newIds = new ArrayList<>();
        Map<String, List<Integer>> newSecIds = new LinkedHashMap<>();
        List<Integer> newGlobalIds = new ArrayList<>();

        for (int rowNumber = 1;; rowNumber++) {
            if (isEndOfFile(s, rowNumber)) {
                break;
            }

            int globalID;

            if (preserveIds && !globalUsedIds.isEmpty()) {
                globalID = globalUsedIds.remove(0);
            } else {
                globalID = MathUtilities.getRandomNegativeInt();
            }

            newGlobalIds.add(globalID);
            KnimeTuple dataTuple = new KnimeTuple(SchemaFactory.createDataSchema());
            Row row = s.getRow(rowNumber);
            Cell idCell = getCell(row, idColumn);
            Cell commentCell = getCell(row, commentColumn);
            Cell agentDetailsCell = getCell(row, agentDetailsColumn);
            Cell matrixDetailsCell = getCell(row, matrixDetailsColumn);
            Cell agentCell = getCell(row, agentColumn);
            Cell matrixCell = getCell(row, matrixColumn);
            Cell depMinCell = getCell(row, depMinColumn);
            Cell depMaxCell = getCell(row, depMaxColumn);
            Cell indepMinCell = getCell(row, indepMinColumn);
            Cell indepMaxCell = getCell(row, indepMaxColumn);
            Cell rmseCell = getCell(row, rmseColumn);
            Cell r2Cell = getCell(row, r2Column);
            Cell aicCell = getCell(row, aicColumn);
            Cell dataPointsCell = getCell(row, dataPointsColumn);

            dataTuple.setValue(TimeSeriesSchema.ATT_CONDID, MathUtilities.getRandomNegativeInt());

            PmmXmlDoc dataInfo = new PmmXmlDoc();
            PmmXmlDoc agentXml = new PmmXmlDoc();
            PmmXmlDoc matrixXml = new PmmXmlDoc();

            if (hasData(commentCell)) {
                dataInfo.add(new MdInfoXml(null, null, getData(commentCell), null, null));
            } else {
                dataInfo.add(new MdInfoXml(null, null, null, null, null));

                if (commentColumn != null) {
                    // warnings.add(MdInfoXml.ATT_COMMENT + " value in row "
                    // + (rowNumber + 1) + " is missing");
                }
            }

            if (hasData(agentCell) && agentMappings.get(getData(agentCell)) != null) {
                agentXml.add(new AgentXml(agentMappings.get(getData(agentCell))));
            } else {
                agentXml.add(new AgentXml());

                if (agentColumn != null) {
                    warnings.add(TimeSeriesSchema.ATT_AGENT + " value in row " + (rowNumber + 1) + " is missing");
                }
            }

            if (hasData(matrixCell) && matrixMappings.get(getData(matrixCell)) != null) {
                matrixXml.add(new MatrixXml(matrixMappings.get(getData(matrixCell))));
            } else {
                matrixXml.add(new MatrixXml());

                if (matrixColumn != null) {
                    warnings.add(TimeSeriesSchema.ATT_MATRIX + " value in row " + (rowNumber + 1) + " is missing");
                }
            }

            if (hasData(agentDetailsCell)) {
                ((AgentXml) agentXml.get(0)).setDetail(getData(agentDetailsCell));
            }

            if (hasData(matrixDetailsCell)) {
                ((MatrixXml) matrixXml.get(0)).setDetail(getData(matrixDetailsCell));
            }

            dataTuple.setValue(TimeSeriesSchema.ATT_MDINFO, dataInfo);
            dataTuple.setValue(TimeSeriesSchema.ATT_AGENT, agentXml);
            dataTuple.setValue(TimeSeriesSchema.ATT_MATRIX, matrixXml);

            PmmXmlDoc miscXML = new PmmXmlDoc();

            for (String column : miscColumns.keySet()) {
                MiscXml misc = new MiscXml((MiscXml) columnMappings.get(column));
                Cell cell = row.getCell(miscColumns.get(column));

                if (hasData(cell)) {
                    try {
                        misc.setValue(Double.parseDouble(getData(cell).replace(",", ".")));
                    } catch (NumberFormatException e) {
                        warnings.add(column + " value in row " + (rowNumber + 1) + " is not valid (" + getData(cell)
                                + ")");
                    }
                } else {
                    warnings.add(column + " value in row " + (rowNumber + 1) + " is missing");
                }

                misc.setOrigUnit(misc.getUnit());
                miscXML.add(misc);
            }

            dataTuple.setValue(TimeSeriesSchema.ATT_MISC, miscXML);

            PmmXmlDoc modelXml = modelTuple.getPmmXml(Model1Schema.ATT_MODELCATALOG);
            PmmXmlDoc paramXml = modelTuple.getPmmXml(Model1Schema.ATT_PARAMETER);
            PmmXmlDoc estXml = modelTuple.getPmmXml(Model1Schema.ATT_ESTMODEL);
            PmmXmlDoc depXml = modelTuple.getPmmXml(Model1Schema.ATT_DEPENDENT);
            PmmXmlDoc indepXml = modelTuple.getPmmXml(Model1Schema.ATT_INDEPENDENT);
            int primId;

            if (preserveIds && !usedIds.isEmpty()) {
                primId = usedIds.remove(0);
            } else {
                primId = MathUtilities.getRandomNegativeInt();
            }

            newIds.add(primId);

            if (modelDepUnit != null && !modelDepUnit.equals(((DepXml) depXml.get(0)).getUnit())) {
                ((DepXml) depXml.get(0)).setUnit(modelDepUnit);
                ((CatalogModelXml) modelXml.get(0)).setId(MathUtilities.getRandomNegativeInt());
            }

            if (hasData(depMinCell)) {
                try {
                    ((DepXml) depXml.get(0)).setMin(Double.parseDouble(getData(depMinCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelDepMin + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(depMinCell) + ")");
                }
            } else if (modelDepMin != null) {
                warnings.add(modelDepMin + " value in row " + (rowNumber + 1) + " is missing");
            }

            if (hasData(depMaxCell)) {
                try {
                    ((DepXml) depXml.get(0)).setMax(Double.parseDouble(getData(depMaxCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelDepMax + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(depMaxCell) + ")");
                }
            } else if (modelDepMax != null) {
                warnings.add(modelDepMax + " value in row " + (rowNumber + 1) + " is missing");
            }

            if (hasData(indepMinCell)) {
                try {
                    ((IndepXml) indepXml.get(0))
                            .setMin(Double.parseDouble(getData(indepMinCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelIndepMin + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(indepMinCell) + ")");
                }
            } else if (modelIndepMin != null) {
                warnings.add(modelIndepMin + " value in row " + (rowNumber + 1) + " is missing");
            }

            if (hasData(indepMaxCell)) {
                try {
                    ((IndepXml) indepXml.get(0))
                            .setMax(Double.parseDouble(getData(indepMaxCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelIndepMax + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(indepMaxCell) + ")");
                }
            } else if (modelIndepMax != null) {
                warnings.add(modelIndepMax + " value in row " + (rowNumber + 1) + " is missing");
            }

            if (modelIndepUnit != null && !modelIndepUnit.equals(((IndepXml) indepXml.get(0)).getUnit())) {
                ((IndepXml) indepXml.get(0)).setUnit(modelIndepUnit);
                ((CatalogModelXml) modelXml.get(0)).setId(MathUtilities.getRandomNegativeInt());
            }

            ((EstModelXml) estXml.get(0)).setId(primId);
            ((EstModelXml) estXml.get(0)).setComment(getData(commentCell));

            if (hasData(rmseCell)) {
                try {
                    ((EstModelXml) estXml.get(0)).setRms(Double.parseDouble(getData(rmseCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelRmse + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(rmseCell) + ")");
                }
            }

            if (hasData(r2Cell)) {
                try {
                    ((EstModelXml) estXml.get(0)).setR2(Double.parseDouble(getData(r2Cell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelR2 + " value in row " + (rowNumber + 1) + " is not valid (" + getData(r2Cell)
                            + ")");
                }
            }

            if (hasData(aicCell)) {
                try {
                    ((EstModelXml) estXml.get(0)).setAic(Double.parseDouble(getData(aicCell).replace(",", ".")));
                } catch (NumberFormatException e) {
                    warnings.add(modelAic + " value in row " + (rowNumber + 1) + " is not valid ("
                            + getData(aicCell) + ")");
                }
            }

            if (hasData(dataPointsCell)) {
                String data = getData(dataPointsCell).replace(".0", "").replace(",0", "");

                try {
                    ((EstModelXml) estXml.get(0)).setDof(Integer.parseInt(data) - paramXml.size());
                } catch (NumberFormatException e) {
                    warnings.add(
                            modelDataPoints + " value in row " + (rowNumber + 1) + " is not valid (" + data + ")");
                }
            }

            if (hasData(idCell)) {
                ((EstModelXml) estXml.get(0)).setName(getData(idCell));
            }

            for (PmmXmlElementConvertable el : paramXml.getElementSet()) {
                ParamXml element = (ParamXml) el;
                String mapping = modelMappings.get(element.getName());

                if (mapping != null) {
                    Cell cell = row.getCell(columns.get(mapping));

                    if (hasData(cell)) {
                        try {
                            element.setValue(Double.parseDouble(getData(cell).replace(",", ".")));
                        } catch (NumberFormatException e) {
                            warnings.add(mapping + " value in row " + (rowNumber + 1) + " is not valid ("
                                    + getData(cell) + ")");
                        }
                    } else {
                        warnings.add(mapping + " value in row " + (rowNumber + 1) + " is missing");
                    }
                }

                String errorMapping = modelParamErrors.get(element.getName());

                if (errorMapping != null) {
                    Cell cell = row.getCell(columns.get(errorMapping));

                    if (hasData(cell)) {
                        try {
                            element.setError(Double.parseDouble(getData(cell).replace(",", ".")));
                        } catch (NumberFormatException e) {
                            warnings.add(errorMapping + " value in row " + (rowNumber + 1) + " is not valid ("
                                    + getData(cell) + ")");
                        }
                    } else {
                        warnings.add(errorMapping + " value in row " + (rowNumber + 1) + " is missing");
                    }
                }
            }

            modelTuple.setValue(Model1Schema.ATT_DEPENDENT, depXml);
            modelTuple.setValue(Model1Schema.ATT_INDEPENDENT, indepXml);
            modelTuple.setValue(Model1Schema.ATT_MODELCATALOG, modelXml);
            modelTuple.setValue(Model1Schema.ATT_PARAMETER, paramXml);
            modelTuple.setValue(Model1Schema.ATT_ESTMODEL, estXml);

            if (secModelTuples.isEmpty()) {
                tuples.put(index + "", new KnimeTuple(SchemaFactory.createM1DataSchema(), modelTuple, dataTuple));
                index++;
            } else {
                for (String param : secModelTuples.keySet()) {
                    KnimeTuple secTuple = secModelTuples.get(param);
                    PmmXmlDoc secParamXml = secTuple.getPmmXml(Model2Schema.ATT_PARAMETER);
                    PmmXmlDoc secDepXml = secTuple.getPmmXml(Model2Schema.ATT_DEPENDENT);
                    PmmXmlDoc secEstXml = secTuple.getPmmXml(Model2Schema.ATT_ESTMODEL);
                    PmmXmlDoc secModelXml = secTuple.getPmmXml(Model2Schema.ATT_MODELCATALOG);
                    PmmXmlDoc secIndepXml = secTuple.getPmmXml(Model2Schema.ATT_INDEPENDENT);
                    String formula = ((CatalogModelXml) secModelXml.get(0)).getFormula();
                    int secID;

                    if (preserveIds && secUsedIds.containsKey(param) && !secUsedIds.get(param).isEmpty()) {
                        secID = secUsedIds.get(param).remove(0);
                    } else {
                        secID = MathUtilities.getRandomNegativeInt();
                    }

                    if (!newSecIds.containsKey(param)) {
                        newSecIds.put(param, new ArrayList<Integer>());
                    }

                    newSecIds.get(param).add(secID);
                    formula = MathUtilities.replaceVariable(formula, ((DepXml) secDepXml.get(0)).getName(), param);
                    ((CatalogModelXml) secModelXml.get(0)).setFormula(formula);
                    ((DepXml) secDepXml.get(0)).setName(param);
                    ((EstModelXml) secEstXml.get(0)).setId(secID);

                    for (PmmXmlElementConvertable el : secParamXml.getElementSet()) {
                        ParamXml element = (ParamXml) el;
                        String mapping = secModelMappings.get(param).get(element.getName());
                        String error = secModelParamErrors.get(param).get(element.getName());

                        if (mapping != null) {
                            Cell cell = row.getCell(columns.get(mapping));

                            if (hasData(cell)) {
                                try {
                                    element.setValue(Double.parseDouble(getData(cell).replace(",", ".")));
                                } catch (NumberFormatException e) {
                                    warnings.add(mapping + " value in row " + (rowNumber + 1) + " is not valid ("
                                            + getData(cell) + ")");
                                }
                            } else {
                                warnings.add(mapping + " value in row " + (rowNumber + 1) + " is missing");
                            }
                        }

                        if (error != null) {
                            Cell cell = row.getCell(columns.get(error));

                            if (hasData(cell)) {
                                try {
                                    element.setError(Double.parseDouble(getData(cell).replace(",", ".")));
                                } catch (NumberFormatException e) {
                                    warnings.add(error + " value in row " + (rowNumber + 1) + " is not valid ("
                                            + getData(cell) + ")");
                                }
                            } else {
                                warnings.add(error + " value in row " + (rowNumber + 1) + " is missing");
                            }
                        }
                    }

                    for (PmmXmlElementConvertable el : secIndepXml.getElementSet()) {
                        IndepXml element = (IndepXml) el;
                        String category = secModelIndepCategories.get(param).get(element.getName());
                        String unit = secModelIndepUnits.get(param).get(element.getName());

                        if (category == null || unit == null) {
                            continue;
                        }

                        if (!category.equals(element.getCategory())) {
                            element.setCategory(category);
                            ((CatalogModelXml) secModelXml.get(0)).setId(MathUtilities.getRandomNegativeInt());
                        }

                        if (!unit.equals(element.getUnit())) {
                            element.setUnit(unit);
                            ((CatalogModelXml) secModelXml.get(0)).setId(MathUtilities.getRandomNegativeInt());
                        }

                        String minColumn = secModelIndepMins.get(param).get(element.getName());
                        String maxColumn = secModelIndepMaxs.get(param).get(element.getName());

                        if (minColumn != null) {
                            Cell minCell = row.getCell(columns.get(minColumn));

                            if (hasData(minCell)) {
                                try {
                                    element.setMin(Double.parseDouble(getData(minCell).replace(",", ".")));
                                } catch (NumberFormatException e) {
                                    warnings.add(minColumn + " value in row " + (rowNumber + 1) + " is not valid ("
                                            + getData(minCell) + ")");
                                }
                            } else {
                                warnings.add(minColumn + " value in row " + (rowNumber + 1) + " is missing");
                            }
                        }

                        if (maxColumn != null) {
                            Cell maxCell = row.getCell(columns.get(maxColumn));

                            if (hasData(maxCell)) {
                                try {
                                    element.setMax(Double.parseDouble(getData(maxCell).replace(",", ".")));
                                } catch (NumberFormatException e) {
                                    warnings.add(maxColumn + " value in row " + (rowNumber + 1) + " is not valid ("
                                            + getData(maxCell) + ")");
                                }
                            } else {
                                warnings.add(maxColumn + " value in row " + (rowNumber + 1) + " is missing");
                            }
                        }
                    }

                    String rmse = secModelRmse.get(param);
                    String r2 = secModelR2.get(param);
                    String aic = secModelAic.get(param);
                    String dataPoints = secModelDataPoints.get(param);

                    if (rmse != null) {
                        Cell cell = row.getCell(columns.get(rmse));

                        if (hasData(cell)) {
                            try {
                                ((EstModelXml) secEstXml.get(0))
                                        .setRms(Double.parseDouble(getData(cell).replace(",", ".")));
                            } catch (NumberFormatException e) {
                                warnings.add(rmse + " value in row " + (rowNumber + 1) + " is not valid ("
                                        + getData(cell) + ")");
                            }
                        } else {
                            warnings.add(rmse + " value in row " + (rowNumber + 1) + " is missing");
                        }
                    }

                    if (r2 != null) {
                        Cell cell = row.getCell(columns.get(r2));

                        if (hasData(cell)) {
                            try {
                                ((EstModelXml) secEstXml.get(0))
                                        .setR2(Double.parseDouble(getData(cell).replace(",", ".")));
                            } catch (NumberFormatException e) {
                                warnings.add(r2 + " value in row " + (rowNumber + 1) + " is not valid ("
                                        + getData(cell) + ")");
                            }
                        } else {
                            warnings.add(r2 + " value in row " + (rowNumber + 1) + " is missing");
                        }
                    }

                    if (aic != null) {
                        Cell cell = row.getCell(columns.get(aic));

                        if (hasData(cell)) {
                            try {
                                ((EstModelXml) secEstXml.get(0))
                                        .setAic(Double.parseDouble(getData(cell).replace(",", ".")));
                            } catch (NumberFormatException e) {
                                warnings.add(aic + " value in row " + (rowNumber + 1) + " is not valid ("
                                        + getData(cell) + ")");
                            }
                        } else {
                            warnings.add(aic + " value in row " + (rowNumber + 1) + " is missing");
                        }
                    }

                    if (dataPoints != null) {
                        Cell cell = row.getCell(columns.get(dataPoints));

                        if (hasData(cell)) {
                            String data = getData(cell).replace(".0", "").replace(",0", "");

                            try {
                                ((EstModelXml) secEstXml.get(0))
                                        .setDof(Integer.parseInt(data) - secParamXml.size());
                            } catch (NumberFormatException e) {
                                warnings.add(dataPoints + " value in row " + (rowNumber + 1) + " is not valid ("
                                        + data + ")");
                            }
                        } else {
                            warnings.add(dataPoints + " value in row " + (rowNumber + 1) + " is missing");
                        }
                    }

                    secTuple.setValue(Model2Schema.ATT_MODELCATALOG, secModelXml);
                    secTuple.setValue(Model2Schema.ATT_PARAMETER, secParamXml);
                    secTuple.setValue(Model2Schema.ATT_DEPENDENT, secDepXml);
                    secTuple.setValue(Model2Schema.ATT_ESTMODEL, secEstXml);
                    secTuple.setValue(Model2Schema.ATT_INDEPENDENT, secIndepXml);
                    secTuple.setValue(Model2Schema.ATT_GLOBAL_MODEL_ID, globalID);

                    tuples.put(index + "", new KnimeTuple(SchemaFactory.createM12DataSchema(),
                            new KnimeTuple(SchemaFactory.createM1DataSchema(), modelTuple, dataTuple), secTuple));
                    index++;
                }
            }
        }

        usedIds.clear();
        usedIds.addAll(newIds);
        secUsedIds.clear();
        secUsedIds.putAll(newSecIds);
        globalUsedIds.clear();
        globalUsedIds.addAll(newGlobalIds);

        return tuples;
    }

    public List<String> getWarnings() {
        return warnings;
    }

    public List<String> getSheets(File file) throws Exception {
        List<String> sheets = new ArrayList<>();
        Workbook workbook = getWorkbook(file);

        for (int i = 0; i < workbook.getNumberOfSheets(); i++) {
            sheets.add(workbook.getSheetName(i));
        }

        return sheets;
    }

    public List<String> getColumns(File file, String sheet) throws Exception {
        Workbook wb = getWorkbook(file);
        Sheet s = wb.getSheet(sheet);

        evaluator = wb.getCreationHelper().createFormulaEvaluator();

        if (s == null) {
            throw new Exception("Sheet not found");
        }

        return new ArrayList<>(getColumns(s).keySet());
    }

    public Set<String> getValuesInColumn(File file, String sheet, String column) throws Exception {
        Set<String> valueSet = new LinkedHashSet<>();
        Workbook wb = getWorkbook(file);
        Sheet s = wb.getSheet(sheet);

        evaluator = wb.getCreationHelper().createFormulaEvaluator();

        if (s == null) {
            throw new Exception("Sheet not found");
        }

        Map<String, Integer> columns = getColumns(s);
        int columnId = columns.get(column);

        for (int i = 1; i <= s.getLastRowNum(); i++) {
            if (s.getRow(i) != null) {
                Cell cell = s.getRow(i).getCell(columnId);

                if (hasData(cell)) {
                    valueSet.add(getData(cell));
                }
            }
        }

        return valueSet;
    }

    public List<Integer> getMissingData(File file, String sheet, String column) throws Exception {
        List<Integer> missing = new ArrayList<>();
        Workbook wb = getWorkbook(file);
        Sheet s = wb.getSheet(sheet);

        evaluator = wb.getCreationHelper().createFormulaEvaluator();

        Map<String, Integer> columns = getColumns(s);
        int columnId = columns.get(column);

        for (int i = 1; i <= s.getLastRowNum(); i++) {
            if (s.getRow(i) != null && !hasData(s.getRow(i).getCell(columnId))) {
                for (int c : columns.values()) {
                    if (hasData(s.getRow(i).getCell(c))) {
                        missing.add(i + 1);
                        break;
                    }
                }
            }
        }

        return missing;
    }

    private Workbook getWorkbook(File file) throws IOException, InvalidFormatException {
        if (file.exists()) {
            try (InputStream in = new FileInputStream(file)) {
                return WorkbookFactory.create(in);
            }
        } else {
            try (InputStream in = new URL(file.getPath()).openStream()) {
                return WorkbookFactory.create(in);
            }
        }
    }

    private Map<String, Integer> getColumns(Sheet sheet) {
        Map<String, Integer> columns = new LinkedHashMap<>();

        for (int i = 0;; i++) {
            Cell cell = sheet.getRow(0).getCell(i);

            if (!hasData(cell)) {
                break;
            }

            columns.put(getData(cell), i);
        }

        return columns;
    }

    private boolean isEndOfFile(Sheet sheet, int i) {
        Row row = sheet.getRow(i);

        if (row == null) {
            return true;
        }

        for (int j = 0;; j++) {
            Cell headerCell = sheet.getRow(0).getCell(j);
            Cell cell = sheet.getRow(i).getCell(j);

            if (!hasData(headerCell)) {
                return true;
            }

            if (hasData(cell)) {
                return false;
            }
        }
    }

    private boolean hasData(Cell cell) {
        return cell != null && !cell.toString().trim().isEmpty();
    }

    private String getData(Cell cell) {
        if (cell != null) {
            if (cell.getCellType() == Cell.CELL_TYPE_FORMULA) {
                CellValue value = evaluator.evaluate(cell);

                switch (value.getCellType()) {
                case Cell.CELL_TYPE_BOOLEAN:
                    return value.getBooleanValue() + "";
                case Cell.CELL_TYPE_NUMERIC:
                    return value.getNumberValue() + "";
                case Cell.CELL_TYPE_STRING:
                    return value.getStringValue();
                default:
                    return "";
                }
            } else {
                return cell.toString().trim();
            }
        }

        return null;
    }

    private Cell getCell(Row row, Integer column) {
        if (column == null) {
            return null;
        }

        return row.getCell(column);
    }

    private boolean hasSameValue(String param, Double value, PmmXmlDoc miscs) {
        for (PmmXmlElementConvertable el : miscs.getElementSet()) {
            MiscXml misc = (MiscXml) el;

            if (misc.getName().equals(param) && !value.equals(misc.getValue())) {
                return false;
            }
        }

        return true;
    }
}