StringBuilder.Remove removes the specified range of characters from this instance.
Imports System
Imports System.Text
Class Sample
Public Shared Sub Main()
Dim str As String = "The quick brown fox jumps over the lazy dog."
Dim sb As New StringBuilder(str)
Console.WriteLine("{0}", sb.ToString())
sb.Remove(10, 6)
Console.WriteLine("{0}", sb.ToString())
End Sub
End Class