Use setStyle to change font size

           
<?xml version="1.0"?>
<mx:Application xmlns:mx="http://www.adobe.com/2006/mxml">
    <mx:Script>
    public function changeLabel(s:String):void {
        s = "myButton" + s;
        this[s].setStyle("fontStyle","italic");
        this[s].setStyle("fontSize","18");
    }
  </mx:Script>
    <mx:Button id="myButton1" click="changeLabel('2')" label="Change Other Button's Styles" />
    <mx:Button id="myButton2" click="changeLabel('1')" label="Change Other Button's Styles" />
</mx:Application>

1.	Use setStyle() method, set it inline, or use Cascading Style Sheets (CSS)
2.	Using setStyle to programmatically manipulate a style property
3.	Use setStyle to change font style
4.	Cast target to a UIComponent before calling the setStyle() method
5.	Use setStyle() method
6.	Using the setStyle() method to apply graphical skins
7.	Using setStyle() method with a trigger
8.	Use the setStyle() method to apply the custom class to the item renderer.
9.	Use getStyle() with effects defined in MXML
10.	Use getStyle() with behaviors defined in MXML
11.	Set a style property inline, and then reads that property with the getStyle() method

Use setStyle to change font size : Style Get Set « Style « Flex

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