You can use the DEFINE system variable as a switch (ON or OFF).
You can change the DEFINE character, if you need the ampersand character (&) without its special meaning.
SQL> select 'Test&Co' as result from dual; Enter value for co: ASDF SQL> set define off SQL> run 1* select 'Test&Co' as result from dual SQL> set define ! SQL> select 'Test&Co' as result from !table; Enter value for table: dual SQL> set define & SQL>
You can exit SQL*Plus and start a new session in order to reset all SQL*Plus variables to their default values.