Example usage for javafx.scene.control RadioMenuItem setToggleGroup

List of usage examples for javafx.scene.control RadioMenuItem setToggleGroup

Introduction

In this page you can find the example usage for javafx.scene.control RadioMenuItem setToggleGroup.

Prototype

@Override
    public final void setToggleGroup(ToggleGroup value) 

Source Link

Usage

From source file:Main.java

@Override
public void start(Stage primaryStage) {
    BorderPane root = new BorderPane();
    Scene scene = new Scene(root, 300, 250, Color.WHITE);

    MenuBar menuBar = new MenuBar();
    menuBar.prefWidthProperty().bind(primaryStage.widthProperty());
    root.setTop(menuBar);/* w ww .jav  a 2s  .c  om*/

    // File menu - new, save, exit
    Menu fileMenu = new Menu("File");
    MenuItem newMenuItem = new MenuItem("New");
    MenuItem saveMenuItem = new MenuItem("Save");
    MenuItem exitMenuItem = new MenuItem("Exit");
    exitMenuItem.setOnAction(actionEvent -> Platform.exit());

    fileMenu.getItems().addAll(newMenuItem, saveMenuItem, new SeparatorMenuItem(), exitMenuItem);

    Menu webMenu = new Menu("Web");
    CheckMenuItem htmlMenuItem = new CheckMenuItem("HTML");
    htmlMenuItem.setSelected(true);
    webMenu.getItems().add(htmlMenuItem);

    CheckMenuItem cssMenuItem = new CheckMenuItem("CSS");
    cssMenuItem.setSelected(true);
    webMenu.getItems().add(cssMenuItem);

    Menu sqlMenu = new Menu("SQL");
    ToggleGroup tGroup = new ToggleGroup();
    RadioMenuItem mysqlItem = new RadioMenuItem("MySQL");
    mysqlItem.setToggleGroup(tGroup);

    RadioMenuItem oracleItem = new RadioMenuItem("Oracle");
    oracleItem.setToggleGroup(tGroup);
    oracleItem.setSelected(true);

    sqlMenu.getItems().addAll(mysqlItem, oracleItem, new SeparatorMenuItem());

    Menu tutorialManeu = new Menu("Tutorial");
    tutorialManeu.getItems().addAll(new CheckMenuItem("Java"), new CheckMenuItem("JavaFX"),
            new CheckMenuItem("Swing"));

    sqlMenu.getItems().add(tutorialManeu);

    menuBar.getMenus().addAll(fileMenu, webMenu, sqlMenu);

    primaryStage.setScene(scene);
    primaryStage.show();
}

From source file:Main.java

private Menu alarmMenu() {
    Menu alarmMenu = new Menu("Alarm");
    RadioMenuItem soundAlarmItem = new RadioMenuItem("Sound Alarm");
    RadioMenuItem stopAlarmItem = new RadioMenuItem("Alarm Off");

    Menu contingencyPlans = new Menu("Plans");
    contingencyPlans.getItems().addAll(new CheckMenuItem("A"), new CheckMenuItem("B"), new CheckMenuItem("C"));
    alarmMenu.getItems().add(contingencyPlans);
    ToggleGroup tGroup = new ToggleGroup();
    soundAlarmItem.setToggleGroup(tGroup);
    stopAlarmItem.setToggleGroup(tGroup);
    stopAlarmItem.setSelected(true);/*from   w w  w.  j  a v a2s.c o  m*/
    alarmMenu.getItems().addAll(soundAlarmItem, stopAlarmItem, new SeparatorMenuItem());
    return alarmMenu;
}

From source file:Main.java

@Override
public void start(Stage stage) {
    stage.setTitle("Menu Sample");
    Scene scene = new Scene(new VBox(), 400, 350);
    scene.setFill(Color.OLDLACE);

    name.setFont(new Font("Verdana Bold", 22));
    binName.setFont(new Font("Arial Italic", 10));
    pic.setFitHeight(150);/*  w  ww. j  av a 2s .com*/
    pic.setPreserveRatio(true);
    description.setWrapText(true);
    description.setTextAlignment(TextAlignment.JUSTIFY);

    shuffle();

    MenuBar menuBar = new MenuBar();

    // --- Graphical elements
    final VBox vbox = new VBox();
    vbox.setAlignment(Pos.CENTER);
    vbox.setSpacing(10);
    vbox.setPadding(new Insets(0, 10, 0, 10));
    vbox.getChildren().addAll(name, binName, pic, description);

    // --- Menu File
    Menu menuFile = new Menu("File");
    MenuItem add = new MenuItem("Shuffle", new ImageView(new Image("src/menusample/new.png")));
    add.setOnAction(new EventHandler<ActionEvent>() {
        public void handle(ActionEvent t) {
            shuffle();
            vbox.setVisible(true);
        }
    });

    MenuItem clear = new MenuItem("Clear");
    clear.setAccelerator(KeyCombination.keyCombination("Ctrl+X"));
    clear.setOnAction(new EventHandler<ActionEvent>() {
        public void handle(ActionEvent t) {
            vbox.setVisible(false);
        }
    });

    MenuItem exit = new MenuItem("Exit");
    exit.setOnAction(new EventHandler<ActionEvent>() {
        public void handle(ActionEvent t) {
            System.exit(0);
        }
    });

    menuFile.getItems().addAll(add, clear, new SeparatorMenuItem(), exit);

    // --- Menu Edit
    Menu menuEdit = new Menu("Edit");
    Menu menuEffect = new Menu("Picture Effect");

    final ToggleGroup groupEffect = new ToggleGroup();
    for (Entry effect : effects) {
        RadioMenuItem itemEffect = new RadioMenuItem((String) effect.getKey());
        itemEffect.setUserData(effect.getValue());
        itemEffect.setToggleGroup(groupEffect);
        menuEffect.getItems().add(itemEffect);
    }

    final MenuItem noEffects = new MenuItem("No Effects");
    noEffects.setDisable(true);
    noEffects.setOnAction(new EventHandler<ActionEvent>() {
        public void handle(ActionEvent t) {
            pic.setEffect(null);
            groupEffect.getSelectedToggle().setSelected(false);
            noEffects.setDisable(true);
        }
    });

    groupEffect.selectedToggleProperty().addListener(new ChangeListener<Toggle>() {
        public void changed(ObservableValue ov, Toggle old_toggle, Toggle new_toggle) {
            if (groupEffect.getSelectedToggle() != null) {
                Effect effect = (Effect) groupEffect.getSelectedToggle().getUserData();
                pic.setEffect(effect);
                noEffects.setDisable(false);
            } else {
                noEffects.setDisable(true);
            }
        }
    });

    menuEdit.getItems().addAll(menuEffect, noEffects);

    // --- Menu View
    Menu menuView = new Menu("View");
    CheckMenuItem titleView = createMenuItem("Title", name);
    CheckMenuItem binNameView = createMenuItem("Binomial name", binName);
    CheckMenuItem picView = createMenuItem("Picture", pic);
    CheckMenuItem descriptionView = createMenuItem("Decsription", description);

    menuView.getItems().addAll(titleView, binNameView, picView, descriptionView);
    menuBar.getMenus().addAll(menuFile, menuEdit, menuView);

    // --- Context Menu
    final ContextMenu cm = new ContextMenu();
    MenuItem cmItem1 = new MenuItem("Copy Image");
    cmItem1.setOnAction(new EventHandler<ActionEvent>() {
        public void handle(ActionEvent e) {
            Clipboard clipboard = Clipboard.getSystemClipboard();
            ClipboardContent content = new ClipboardContent();
            content.putImage(pic.getImage());
            clipboard.setContent(content);
        }
    });

    cm.getItems().add(cmItem1);
    pic.addEventHandler(MouseEvent.MOUSE_CLICKED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            if (e.getButton() == MouseButton.SECONDARY)
                cm.show(pic, e.getScreenX(), e.getScreenY());
        }
    });

    ((VBox) scene.getRoot()).getChildren().addAll(menuBar, vbox);

    stage.setScene(scene);
    stage.show();
}

From source file:pl.baczkowicz.mqttspy.ui.controllers.NewPublicationController.java

public static void updateScriptList(final List<Script> scripts, final Menu scriptsMenu,
        final ToggleGroup toggleGroup, final String format, final EventHandler<ActionEvent> eventHandler) {
    while (scriptsMenu.getItems().size() > 0) {
        scriptsMenu.getItems().remove(0);
    }/*from w  w  w.j a v a2s  .c  o m*/

    if (scripts.size() > 0) {
        for (final Script script : scripts) {
            final RadioMenuItem item = new RadioMenuItem(String.format(format, script.getName()));
            item.setOnAction(eventHandler);
            item.setToggleGroup(toggleGroup);
            item.setUserData(script);

            scriptsMenu.getItems().add(item);
        }
    }
}

From source file:qupath.lib.gui.panels.survival.KaplanMeierDisplay.java

@SuppressWarnings("unchecked")
private void generatePlot() {

    KaplanMeierDisplay.ScoreData newScoreData = scoreData;

    // If we have a hierarchy, update the scores with the most recent data
    if (hierarchy != null) {
        List<TMACoreObject> cores = PathObjectTools.getTMACoreObjects(hierarchy, false);
        double[] survival = new double[cores.size()];
        boolean[] censored = new boolean[cores.size()];
        double[] scores = new double[cores.size()];

        //            // Optionally sort by scores... helps a bit when debugging e.g. p-values, Hazard ratios etc.
        //            cores.sort((c1, c2) -> Double.compare(c1.getMeasurementList().getMeasurementValue(scoreColumn), c2.getMeasurementList().getMeasurementValue(scoreColumn)));

        //            scoreColumn = "Positive %";
        //         scoreColumn = "RoughScore";
        for (int i = 0; i < cores.size(); i++) {
            TMACoreObject core = cores.get(i);
            MeasurementList ml = core.getMeasurementList();
            survival[i] = core.getMeasurementList().getMeasurementValue(survivalColumn);
            double censoredValue = core.getMeasurementList().getMeasurementValue(censoredColumn);
            boolean hasCensoredValue = !Double.isNaN(censoredValue)
                    && (censoredValue == 0 || censoredValue == 1);
            censored[i] = censoredValue != 0;
            if (!hasCensoredValue) {
                // If we don't have a censored value, ensure we mask out everything else
                scores[i] = Double.NaN;
                survival[i] = Double.NaN;
            } else if (ml.containsNamedMeasurement(scoreColumn))
                // Get the score if we can
                scores[i] = ml.getMeasurementValue(scoreColumn);
            else {
                //               // Try to compute score if we need to
                //               Map<String, Number> map = ROIMeaningfulMeasurements.getPathClassSummaryMeasurements(core.getChildObjects(), true);
                //               Number value = map.get(scoreColumn);
                //               if (value == null)
                scores[i] = Double.NaN;
                //               else
                //                  scores[i] = value.doubleValue();
            }//from  w w  w.  ja  va  2  s . co m
        }
        // Mask out any scores that don't have associated survival data
        for (int i = 0; i < survival.length; i++) {
            if (Double.isNaN(survival[i]))
                scores[i] = Double.NaN;
        }

        newScoreData = new ScoreData(scores, survival, censored);

    }

    if (newScoreData == null || newScoreData.scores.length == 0)
        return;

    //         KaplanMeier kmHigh = new KaplanMeier("Above threshold");
    //         KaplanMeier kmLow = new KaplanMeier("Below threshold");

    double[] quartiles = StatisticsHelper.getQuartiles(newScoreData.scores);
    double q1 = quartiles[0];
    double median = quartiles[1];
    double q3 = quartiles[2];
    double[] thresholds;
    if (params != null) {
        Object thresholdMethod = params.getChoiceParameterValue("scoreThresholdMethod");
        if (thresholdMethod.equals("Median")) {
            //               panelParams.setNumericParameterValue("scoreThreshold", median);
            //               ((DoubleParameter)params.getParameters().get("scoreThreshold")).setValue(median); // TODO: UPDATE DIALOG!
            thresholds = new double[] { median };
        } else if (thresholdMethod.equals("Tertiles")) {
            //                  ((DoubleParameter)params.getParameters().get("scoreThreshold")).setValue(median); // TODO: UPDATE DIALOG!
            thresholds = StatisticsHelper.getTertiles(newScoreData.scores);
        } else if (thresholdMethod.equals("Quartiles")) {
            //               ((DoubleParameter)params.getParameters().get("scoreThreshold")).setValue(median); // TODO: UPDATE DIALOG!
            thresholds = new double[] { q1, median, q3 };
        } else if (thresholdMethod.equals("Manual (1)")) {
            thresholds = new double[] { params.getDoubleParameterValue("threshold1") };
        } else if (thresholdMethod.equals("Manual (2)")) {
            thresholds = new double[] { params.getDoubleParameterValue("threshold1"),
                    params.getDoubleParameterValue("threshold2") };
        } else //if (thresholdMethod.equals("Manual (3)")) {
            thresholds = new double[] { params.getDoubleParameterValue("threshold1"),
                    params.getDoubleParameterValue("threshold2"),
                    params.getDoubleParameterValue("threshold3") };
    } else
        thresholds = new double[] { median };

    double minVal = Double.POSITIVE_INFINITY;
    double maxVal = Double.NEGATIVE_INFINITY;
    int numNonNaN = 0;
    for (double d : newScoreData.scores) {
        if (Double.isNaN(d))
            continue;
        if (d < minVal)
            minVal = d;
        if (d > maxVal)
            maxVal = d;
        numNonNaN++;
    }
    boolean scoresValid = maxVal > minVal; // If not this, we don't have valid scores that we can work with

    double maxTimePoint = 0;
    for (double d : newScoreData.survival) {
        if (Double.isNaN(d))
            continue;
        if (d > maxTimePoint)
            maxTimePoint = d;
    }
    if (panelParams != null
            && maxTimePoint > ((IntParameter) params.getParameters().get("censorTimePoints")).getUpperBound()) {
        panelParams.setNumericParameterValueRange("censorTimePoints", 0, Math.ceil(maxTimePoint));
    }

    // Optionally censor at specified time
    double censorThreshold = params == null ? maxTimePoint : params.getIntParameterValue("censorTimePoints");

    // Compute log-rank p-values for *all* possible thresholds
    // Simultaneously determine the threshold that yields the lowest p-value, 
    // resolving ties in favour of a more even split between high/low numbers of events
    boolean pValuesChanged = false;
    if (calculateAllPValues) {
        if (!(pValues != null && pValueThresholds != null && newScoreData.equals(scoreData)
                && censorThreshold == lastPValueCensorThreshold)) {
            Map<Double, Double> mapLogRank = new TreeMap<>();
            Set<Double> setObserved = new HashSet<>();
            for (int i = 0; i < newScoreData.scores.length; i++) {
                Double d = newScoreData.scores[i];
                boolean observed = !newScoreData.censored[i] && newScoreData.survival[i] < censorThreshold;
                if (observed)
                    setObserved.add(d);
                if (mapLogRank.containsKey(d))
                    continue;
                List<KaplanMeierData> kmsTemp = splitByThresholds(newScoreData, new double[] { d },
                        censorThreshold, false);
                //               if (kmsTemp.get(1).nObserved() == 0 || kmsTemp.get(1).nObserved() == 0)
                //                  continue;
                LogRankResult test = LogRankTest.computeLogRankTest(kmsTemp.get(0), kmsTemp.get(1));
                double pValue = test.getPValue();
                //                  double pValue = test.hazardRatio < 1 ? test.hazardRatio : 1.0/test.hazardRatio; // Checking usefulness of Hazard ratios...
                if (!Double.isFinite(pValue))
                    continue;
                //               if (!Double.isFinite(test.getHazardRatio())) {
                ////                  continue;
                //                  pValue = Double.NaN;
                //               }
                mapLogRank.put(d, pValue);
            }
            pValueThresholds = new double[mapLogRank.size()];
            pValues = new double[mapLogRank.size()];
            pValueThresholdsObserved = new boolean[mapLogRank.size()];
            int count = 0;
            for (Entry<Double, Double> entry : mapLogRank.entrySet()) {
                pValueThresholds[count] = entry.getKey();
                pValues[count] = entry.getValue();
                if (setObserved.contains(entry.getKey()))
                    pValueThresholdsObserved[count] = true;
                count++;
            }

            // Find the longest 'significant' stretch
            int maxSigCount = 0;
            int maxSigInd = -1;
            int sigCurrent = 0;
            int[] sigCount = new int[pValues.length];
            for (int i = 0; i < pValues.length; i++) {
                if (pValues[i] < 0.05) {
                    sigCurrent++;
                    sigCount[i] = sigCurrent;
                    if (sigCurrent > maxSigCount) {
                        maxSigCount = sigCurrent;
                        maxSigInd = i;
                    }
                } else
                    sigCurrent = 0;
            }
            if (maxSigCount == 0) {
                logger.info("No p-values < 0.05");
            } else {
                double minThresh = maxSigInd - maxSigCount < 0 ? pValueThresholds[0] - 0.0000001
                        : pValueThresholds[maxSigInd - maxSigCount];
                double maxThresh = pValueThresholds[maxSigInd];
                int nBetween = 0;
                int nBetweenObserved = 0;
                for (int i = 0; i < newScoreData.scores.length; i++) {
                    if (newScoreData.scores[i] > minThresh && newScoreData.scores[i] <= maxThresh) {
                        nBetween++;
                        if (newScoreData.survival[i] < censorThreshold && !newScoreData.censored[i])
                            nBetweenObserved++;
                    }
                }
                logger.info("Longest stretch of p-values < 0.05: {} - {} ({} entries, {} observed)", minThresh,
                        maxThresh, nBetween, nBetweenObserved);
            }

            pValuesSmoothed = new double[pValues.length];
            Arrays.fill(pValuesSmoothed, Double.NaN);
            int n = (pValues.length / 20) * 2 + 1;
            logger.info("Smoothing log-rank test p-values by " + n);
            for (int i = n / 2; i < pValues.length - n / 2; i++) {
                double sum = 0;
                for (int k = i - n / 2; k < i - n / 2 + n; k++) {
                    sum += pValues[k];
                }
                pValuesSmoothed[i] = sum / n;
            }
            //               for (int i = 0; i < pValues.length; i++) {
            //                  double sum = 0;
            //                  for (int k = Math.max(0, i-n/2); k < Math.min(pValues.length, i-n/2+n); k++) {
            //                     sum += pValues[k];
            //                  }
            //                  pValuesSmoothed[i] = sum/n;
            //               }
            //               pValues = pValuesSmoothed;

            lastPValueCensorThreshold = censorThreshold;
            pValuesChanged = true;
        }
    } else {
        lastPValueCensorThreshold = Double.NaN;
        pValueThresholds = null;
        pValues = null;
    }

    //            if (params != null && !Double.isNaN(bestThreshold) && (params.getChoiceParameterValue("scoreThresholdMethod").equals("Lowest p-value")))
    if (params != null && (params.getChoiceParameterValue("scoreThresholdMethod").equals("Lowest p-value"))) {
        int bestIdx = -1;
        double bestPValue = Double.POSITIVE_INFINITY;
        for (int i = pValueThresholds.length / 10; i < pValueThresholds.length * 9 / 10; i++) {
            if (pValues[i] < bestPValue) {
                bestIdx = i;
                bestPValue = pValues[i];
            }
        }
        thresholds = bestIdx >= 0 ? new double[] { pValueThresholds[bestIdx] } : new double[0];
    } else if (params != null
            && (params.getChoiceParameterValue("scoreThresholdMethod").equals("Lowest smoothed p-value"))) {
        int bestIdx = -1;
        double bestPValue = Double.POSITIVE_INFINITY;
        for (int i = pValueThresholds.length / 10; i < pValueThresholds.length * 9 / 10; i++) {
            if (pValuesSmoothed[i] < bestPValue) {
                bestIdx = i;
                bestPValue = pValuesSmoothed[i];
            }
        }
        thresholds = bestIdx >= 0 ? new double[] { pValueThresholds[bestIdx] } : new double[0];
    }

    // Split into different curves using the provided thresholds
    List<KaplanMeierData> kms = splitByThresholds(newScoreData, thresholds, censorThreshold,
            params != null && "Quartiles".equals(params.getChoiceParameterValue("scoreThresholdMethod")));

    //         for (KaplanMeier km : kms)
    //            km.censorAtTime(censorThreshold);
    ////         kmHigh.censorAtTime(censorThreshold);
    ////         kmLow.censorAtTime(censorThreshold);

    //         logger.info("High: " + kmHigh.toString());
    //         logger.info("Low: " + kmLow.toString());
    //         logger.info("Log rank comparison: {}", LogRankTest.computeLogRankTest(kmLow, kmHigh));

    if (plotter == null) {
        plotter = new KaplanMeierChartWrapper(survivalColumn + " time");
        //            plotter.setBorder(BorderFactory.createTitledBorder("Survival plot"));
        //            plotter.getCanvas().setWidth(300);
        //            plotter.getCanvas().setHeight(300);
    }
    KaplanMeierData[] kmArray = new KaplanMeierData[kms.size()];
    plotter.setKaplanMeierCurves(survivalColumn + " time", kms.toArray(kmArray));
    tableModel.setSurvivalCurves(thresholds,
            params != null && params.getChoiceParameterValue("scoreThresholdMethod").equals("Lowest p-value"),
            kmArray);

    // Bar width determined using 'Freedman and Diaconis' rule' (but overridden if this gives < 16 bins...)
    double barWidth = (2 * q3 - q1) * Math.pow(numNonNaN, -1.0 / 3.0);
    int nBins = 100;
    if (!Double.isNaN(barWidth))
        barWidth = (int) Math.max(16, Math.ceil((maxVal - minVal) / barWidth));
    Histogram histogram = scoresValid ? new Histogram(newScoreData.scores, nBins) : null;
    if (histogramPanel == null) {
        GridPane paneHistogram = new GridPane();
        histogramPanel = new HistogramPanelFX();
        histogramPanel.getChart().setAnimated(false);
        histogramWrapper = new ThresholdedChartWrapper(histogramPanel.getChart());
        for (ObservableNumberValue val : threshProperties)
            histogramWrapper.addThreshold(val, ColorToolsFX.getCachedColor(240, 0, 0, 128));
        histogramWrapper.getPane().setPrefHeight(150);
        paneHistogram.add(histogramWrapper.getPane(), 0, 0);
        Tooltip.install(histogramPanel.getChart(), new Tooltip("Distribution of scores"));
        GridPane.setHgrow(histogramWrapper.getPane(), Priority.ALWAYS);
        GridPane.setVgrow(histogramWrapper.getPane(), Priority.ALWAYS);

        NumberAxis xAxis = new NumberAxis();
        xAxis.setLabel("Score threshold");
        NumberAxis yAxis = new NumberAxis();
        yAxis.setLowerBound(0);
        yAxis.setUpperBound(1);
        yAxis.setTickUnit(0.1);
        yAxis.setAutoRanging(false);
        yAxis.setLabel("P-value");
        chartPValues = new LineChart<>(xAxis, yAxis);
        chartPValues.setAnimated(false);
        chartPValues.setLegendVisible(false);

        // Make chart so it can be navigated
        ChartToolsFX.makeChartInteractive(chartPValues, xAxis, yAxis);
        pValuesChanged = true;
        Tooltip.install(chartPValues, new Tooltip(
                "Distribution of p-values (log-rank test) comparing low vs. high for all possible score thresholds"));
        //            chartPValues.getYAxis().setAutoRanging(false);
        pValuesWrapper = new ThresholdedChartWrapper(chartPValues);
        for (ObservableNumberValue val : threshProperties)
            pValuesWrapper.addThreshold(val, ColorToolsFX.getCachedColor(240, 0, 0, 128));

        pValuesWrapper.getPane().setPrefHeight(150);
        paneHistogram.add(pValuesWrapper.getPane(), 0, 1);
        GridPane.setHgrow(pValuesWrapper.getPane(), Priority.ALWAYS);
        GridPane.setVgrow(pValuesWrapper.getPane(), Priority.ALWAYS);

        ContextMenu popup = new ContextMenu();
        ChartToolsFX.addChartExportMenu(chartPValues, popup);

        RadioMenuItem miZoomY1 = new RadioMenuItem("0-1");
        miZoomY1.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(1);
            yAxis.setTickUnit(0.2);
        });
        RadioMenuItem miZoomY05 = new RadioMenuItem("0-0.5");
        miZoomY05.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(0.5);
            yAxis.setTickUnit(0.1);
        });
        RadioMenuItem miZoomY02 = new RadioMenuItem("0-0.2");
        miZoomY02.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(0.2);
            yAxis.setTickUnit(0.05);
        });
        RadioMenuItem miZoomY01 = new RadioMenuItem("0-0.1");
        miZoomY01.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(0.1);
            yAxis.setTickUnit(0.05);
        });
        RadioMenuItem miZoomY005 = new RadioMenuItem("0-0.05");
        miZoomY005.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(0.05);
            yAxis.setTickUnit(0.01);
        });
        RadioMenuItem miZoomY001 = new RadioMenuItem("0-0.01");
        miZoomY001.setOnAction(e -> {
            yAxis.setAutoRanging(false);
            yAxis.setUpperBound(0.01);
            yAxis.setTickUnit(0.005);
        });
        ToggleGroup tgZoom = new ToggleGroup();
        miZoomY1.setToggleGroup(tgZoom);
        miZoomY05.setToggleGroup(tgZoom);
        miZoomY02.setToggleGroup(tgZoom);
        miZoomY01.setToggleGroup(tgZoom);
        miZoomY005.setToggleGroup(tgZoom);
        miZoomY001.setToggleGroup(tgZoom);
        Menu menuZoomY = new Menu("Set y-axis range");
        menuZoomY.getItems().addAll(miZoomY1, miZoomY05, miZoomY02, miZoomY01, miZoomY005, miZoomY001);

        MenuItem miCopyData = new MenuItem("Copy chart data");
        miCopyData.setOnAction(e -> {
            String dataString = ChartToolsFX.getChartDataAsString(chartPValues);
            ClipboardContent content = new ClipboardContent();
            content.putString(dataString);
            Clipboard.getSystemClipboard().setContent(content);
        });

        popup.getItems().addAll(miCopyData, menuZoomY);
        chartPValues.setOnContextMenuRequested(e -> {
            popup.show(chartPValues, e.getScreenX(), e.getScreenY());
        });

        for (int col = 0; col < tableModel.getColumnCount(); col++) {
            TableColumn<Integer, String> column = new TableColumn<>(tableModel.getColumnName(col));
            int colNumber = col;
            column.setCellValueFactory(
                    new Callback<CellDataFeatures<Integer, String>, ObservableValue<String>>() {
                        @Override
                        public ObservableValue<String> call(CellDataFeatures<Integer, String> p) {
                            return new SimpleStringProperty(
                                    (String) tableModel.getValueAt(p.getValue(), colNumber));
                        }
                    });

            column.setCellFactory(new Callback<TableColumn<Integer, String>, TableCell<Integer, String>>() {

                @Override
                public TableCell<Integer, String> call(TableColumn<Integer, String> param) {
                    TableCell<Integer, String> cell = new TableCell<Integer, String>() {
                        @Override
                        protected void updateItem(String item, boolean empty) {
                            super.updateItem(item, empty);
                            setText(item);
                            setTooltip(new Tooltip(item));
                        }
                    };
                    return cell;
                }
            });

            table.getColumns().add(column);
        }
        table.setPrefHeight(250);
        table.setColumnResizePolicy(TableView.CONSTRAINED_RESIZE_POLICY);
        table.maxHeightProperty().bind(table.prefHeightProperty());

        params = new ParameterList();
        //         maxTimePoint = 0;
        //         for (TMACoreObject core : hierarchy.getTMAGrid().getTMACoreList()) {
        //            double os = core.getMeasurementList().getMeasurementValue(TMACoreObject.KEY_OVERALL_SURVIVAL);
        //            double rfs = core.getMeasurementList().getMeasurementValue(TMACoreObject.KEY_RECURRENCE_FREE_SURVIVAL);
        //            if (os > maxTimePoint)
        //               maxTimePoint = os;
        //            if (rfs > maxTimePoint)
        //               maxTimePoint = rfs;
        //         }
        params.addIntParameter("censorTimePoints", "Max censored time", (int) (censorThreshold + 0.5), null, 0,
                (int) Math.ceil(maxTimePoint), "Latest time point beyond which data will be censored");
        //            params.addChoiceParameter("scoreThresholdMethod", "Threshold method", "Manual", Arrays.asList("Manual", "Median", "Log-rank test"));
        if (calculateAllPValues)
            // Don't include "Lowest smoothed p-value" - it's not an established method and open to misinterpretation...
            params.addChoiceParameter("scoreThresholdMethod", "Threshold method", "Median",
                    Arrays.asList("Manual (1)", "Manual (2)", "Manual (3)", "Median", "Tertiles", "Quartiles",
                            "Lowest p-value"));
        //            params.addChoiceParameter("scoreThresholdMethod", "Threshold method", "Median", Arrays.asList("Manual (1)", "Manual (2)", "Manual (3)", "Median", "Tertiles", "Quartiles", "Lowest p-value", "Lowest smoothed p-value"));
        else
            params.addChoiceParameter("scoreThresholdMethod", "Threshold method", "Median",
                    Arrays.asList("Manual (1)", "Manual (2)", "Manual (3)", "Median", "Tertiles", "Quartiles"));
        params.addDoubleParameter("threshold1", "Threshold 1",
                thresholds.length > 0 ? thresholds[0] : (minVal + maxVal) / 2, null,
                "Threshold to distinguish between patient groups");
        params.addDoubleParameter("threshold2", "Threshold 2",
                thresholds.length > 1 ? thresholds[1] : (minVal + maxVal) / 2, null,
                "Threshold to distinguish between patient groups");
        params.addDoubleParameter("threshold3", "Threshold 3",
                thresholds.length > 2 ? thresholds[2] : (minVal + maxVal) / 2, null,
                "Threshold to distinguish between patient groups");
        params.addBooleanParameter("showAtRisk", "Show at risk", plotter.getShowAtRisk(),
                "Show number of patients at risk below the plot");
        params.addBooleanParameter("showTicks", "Show censored ticks", plotter.getShowCensoredTicks(),
                "Show ticks to indicate censored data");
        params.addBooleanParameter("showKey", "Show key", plotter.getShowKey(),
                "Show key indicating display of each curve");
        //            params.addBooleanParameter("useColor", "Use color", plotter.getUseColor(), "Show each curve in a different color");
        //         params.addBooleanParameter("useStrokes", "Use strokes", plotter.getUseStrokes(), "Show each curve with a differed line stroke");
        // Hide threshold parameters if threshold can't be used
        if (!scoresValid) {
            //               params.setHiddenParameters(true, "scoreThresholdMethod", "scoreThreshold");
            histogramPanel.getChart().setVisible(false);
        }
        panelParams = new ParameterPanelFX(params);
        panelParams.addParameterChangeListener(this);
        updateThresholdsEnabled();

        for (int i = 0; i < threshProperties.length; i++) {
            String p = "threshold" + (i + 1);
            threshProperties[i].addListener((v, o, n) -> {
                if (interactiveThresholds()) {
                    // Need to do a decent double check with tolerance to text field value changing while typing
                    if (!GeneralTools.almostTheSame(params.getDoubleParameterValue(p), n.doubleValue(), 0.0001))
                        panelParams.setNumericParameterValue(p, n);
                }
            });
        }

        BorderPane paneBottom = new BorderPane();
        TitledPane paneOptions = new TitledPane("Options", panelParams.getPane());
        //            paneOptions.setCollapsible(false);
        Pane paneCanvas = new StackPane();
        paneCanvas.getChildren().add(plotter.getCanvas());

        GridPane paneLeft = new GridPane();
        paneLeft.add(paneOptions, 0, 0);
        paneLeft.add(table, 0, 1);
        GridPane.setHgrow(paneOptions, Priority.ALWAYS);
        GridPane.setHgrow(table, Priority.ALWAYS);
        paneBottom.setLeft(paneLeft);
        paneBottom.setCenter(paneHistogram);

        paneMain.setCenter(paneCanvas);
        paneMain.setBottom(paneBottom);

        paneMain.setPadding(new Insets(10, 10, 10, 10));
    } else if (thresholds.length > 0) {
        // Ensure the sliders/text fields are set sensibly
        if (!GeneralTools.almostTheSame(thresholds[0], params.getDoubleParameterValue("threshold1"), 0.0001)) {
            panelParams.setNumericParameterValue("threshold1", thresholds[0]);
        }
        if (thresholds.length > 1 && !GeneralTools.almostTheSame(thresholds[1],
                params.getDoubleParameterValue("threshold2"), 0.0001)) {
            panelParams.setNumericParameterValue("threshold2", thresholds[1]);
        }
        if (thresholds.length > 2 && !GeneralTools.almostTheSame(thresholds[2],
                params.getDoubleParameterValue("threshold3"), 0.0001)) {
            panelParams.setNumericParameterValue("threshold3", thresholds[2]);
        }
    }

    if (histogram != null) {
        histogramPanel.getHistogramData()
                .setAll(HistogramPanelFX.createHistogramData(histogram, false, (Color) null));
        histogramPanel.getChart().getXAxis().setLabel(scoreColumn);
        histogramPanel.getChart().getYAxis().setLabel("Count");

        ChartToolsFX.addChartExportMenu(histogramPanel.getChart(), null);

        //            histogramWrapper.setVerticalLines(thresholds, ColorToolsFX.getCachedColor(240, 0, 0, 128));
        // Deal with threshold adjustment
        //            histogramWrapper.getThresholds().addListener((Observable o) -> generatePlot());
    }

    if (pValues != null) {
        // TODO: Raise earlier where p-value calculation is
        if (pValuesChanged) {
            ObservableList<XYChart.Data<Number, Number>> data = FXCollections.observableArrayList();
            for (int i = 0; i < pValueThresholds.length; i++) {
                double pValue = pValues[i];
                if (Double.isNaN(pValue))
                    continue;
                data.add(new XYChart.Data<>(pValueThresholds[i], pValue, pValueThresholdsObserved[i]));
            }

            ObservableList<XYChart.Data<Number, Number>> dataSmoothed = null;
            if (pValuesSmoothed != null) {
                dataSmoothed = FXCollections.observableArrayList();
                for (int i = 0; i < pValueThresholds.length; i++) {
                    double pValueSmoothed = pValuesSmoothed[i];
                    if (Double.isNaN(pValueSmoothed))
                        continue;
                    dataSmoothed.add(new XYChart.Data<>(pValueThresholds[i], pValueSmoothed));
                }
            }

            // Don't bother showing the smoothed data... it tends to get in the way...
            //            if (dataSmoothed != null)
            //               chartPValues.getData().setAll(new XYChart.Series<>("P-values", data), new XYChart.Series<>("Smoothed P-values", dataSmoothed));
            //            else
            chartPValues.getData().setAll(new XYChart.Series<>("P-values", data));

            // Add line to show 0.05 significance threshold
            if (pValueThresholds.length > 1) {
                Data<Number, Number> sigData1 = new Data<>(pValueThresholds[0], 0.05);
                Data<Number, Number> sigData2 = new Data<>(pValueThresholds[pValueThresholds.length - 1], 0.05);
                XYChart.Series<Number, Number> dataSignificant = new XYChart.Series<>("Signficance 0.05",
                        FXCollections.observableArrayList(sigData1, sigData2));
                chartPValues.getData().add(dataSignificant);
                sigData1.getNode().setVisible(false);
                sigData2.getNode().setVisible(false);
            }

            //               chartPValues.getData().get(0).getNode().setVisible(true);

            //               pValuesWrapper.clearThresholds();
            for (XYChart.Data<Number, Number> dataPoint : data) {
                if (!Boolean.TRUE.equals(dataPoint.getExtraValue()))
                    dataPoint.getNode().setVisible(false);
            }
            //            if (dataSmoothed != null) {
            //               for (XYChart.Data<Number, Number> dataPoint : dataSmoothed) {
            //                  dataPoint.getNode().setVisible(false);
            //               }
            //               chartPValues.getData().get(1).getNode().setOpacity(0.5);
            //            }

            //               int count = 0;               
            //               for (int i = 0; i < pValueThresholds.length; i++) {
            //                  double pValue = pValues[i];
            //                  if (Double.isNaN(pValue))
            //                     continue;
            //                  boolean observed = pValueThresholdsObserved[i];
            ////                  if (observed)
            ////                     pValuesWrapper.addThreshold(new ReadOnlyDoubleWrapper(pValueThresholds[i]), Color.rgb(0, 0, 0, 0.05));
            //                  
            //                  if (!observed) {
            ////                     StackPane pane = (StackPane)data.get(count).getNode();
            ////                     pane.setEffect(new DropShadow());
            //                     data.get(count).getNode().setVisible(false);
            //                  }
            //                  count++;
            //               }
        }

        for (int i = 0; i < threshProperties.length; i++) {
            if (i < thresholds.length)
                threshProperties[i].set(thresholds[i]);
            else
                threshProperties[i].set(Double.NaN);
        }
        boolean isInteractive = interactiveThresholds();
        histogramWrapper.setIsInteractive(isInteractive);
        pValuesWrapper.setIsInteractive(isInteractive);

        chartPValues.setVisible(true);
    }
    //         else
    //            chartPValues.setVisible(false);

    // Store values for next time
    scoreData = newScoreData;
}

From source file:snpviewer.SnpViewer.java

@Override
public void initialize(URL url, ResourceBundle rb) {
    labelSplitPane.setDividerPositions();
    chromSplitPane.setDividerPositions();
    Pane lpane = (Pane) horizontalSplit.getItems().get(0);
    SplitPane.setResizableWithParent(lpane, false);
    //mnemonics/shortcuts for menus        
    mainMenu.useSystemMenuBarProperty().set(true);
    fileMenu.setMnemonicParsing(true);/*w w w. j  a  va  2  s .c o m*/
    sampleMenu.setMnemonicParsing(true);
    goMenu.setMnemonicParsing(true);
    helpMenu.setMnemonicParsing(true);
    newProjectMenu.setAccelerator(new KeyCodeCombination(KeyCode.N, KeyCombination.SHORTCUT_DOWN));
    loadProjectMenu.setAccelerator(new KeyCodeCombination(KeyCode.L, KeyCombination.SHORTCUT_DOWN));
    addAffSampleMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.A, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    addUnSampleMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.U, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    nextChromMenu.setAccelerator(new KeyCodeCombination(KeyCode.EQUALS, KeyCombination.SHORTCUT_DOWN));
    prevChromMenu.setAccelerator(new KeyCodeCombination(KeyCode.MINUS, KeyCombination.SHORTCUT_DOWN));
    firstChromMenu.setAccelerator(new KeyCodeCombination(KeyCode.DIGIT1, KeyCombination.SHORTCUT_DOWN));
    lastChromMenu.setAccelerator(new KeyCodeCombination(KeyCode.DIGIT0, KeyCombination.SHORTCUT_DOWN));
    redrawMenu.setAccelerator(new KeyCodeCombination(KeyCode.R, KeyCombination.SHORTCUT_DOWN));
    cacheChromsMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.C, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    saveToPngMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.S, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    autoFindRegions.setAccelerator(new KeyCodeCombination(KeyCode.F, KeyCombination.SHORTCUT_DOWN));
    //need to disable hideSavedRegionsMenu accelerator for linux - doesn't work for check menus
    hideSavedRegionsMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.H, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    clearSavedRegionsMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.X, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    displaySavedsRegionsMenu.setAccelerator(new KeyCodeCombination(KeyCode.T, KeyCombination.SHORTCUT_DOWN));
    outputSavedRegionsMenu.setAccelerator(new KeyCodeCombination(KeyCode.O, KeyCombination.SHORTCUT_DOWN));
    removeSampleMenu.setAccelerator(
            new KeyCodeCombination(KeyCode.R, KeyCombination.SHORTCUT_DOWN, KeyCombination.SHIFT_DOWN));
    //set radio menu item toggle group
    ArrayList<RadioMenuItem> callQualityRadios = new ArrayList<>(
            Arrays.asList(noFilteringRadio, filter99, filter95, filter90, filter85));
    ToggleGroup callQualityToggle = new ToggleGroup();
    for (RadioMenuItem r : callQualityRadios) {
        r.setToggleGroup(callQualityToggle);
    }
    noFilteringRadio.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            setQualityFilter(null);
        }
    });

    filter99.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            setQualityFilter(0.01);
        }
    });

    filter95.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            setQualityFilter(0.05);
        }
    });

    filter90.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            setQualityFilter(0.10);
        }
    });

    filter85.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            setQualityFilter(0.15);
        }
    });

    nextChromMenu.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            selectNextChromosome(true);
        }
    });

    prevChromMenu.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            selectNextChromosome(false);
        }
    });

    firstChromMenu.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            if (!cancelButton.isDisabled()) {
                cancelButton.fire();
            }
            if (!chromosomeSelector.isDisabled()) {

                chromosomeSelector.getSelectionModel().selectFirst();
            }
        }
    });

    lastChromMenu.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            if (!cancelButton.isDisabled()) {
                cancelButton.fire();
            }
            if (!chromosomeSelector.isDisabled()) {
                chromosomeSelector.getSelectionModel().selectLast();
            }
        }
    });

    hideSavedRegionsMenu.setOnAction(new EventHandler() {
        @Override
        public void handle(Event ev) {
            showHideSavedRegions();
        }
    });

    colorComp.addAll(Arrays.asList(colorComponants));

    //selection context menu
    final ContextMenu scm = new ContextMenu();
    final MenuItem scmItem1 = new MenuItem("Display Flanking SNP IDs");
    scmItem1.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            /* get coordinates of selection and report back
             * flanking snp ids and coordinates
             */
            displayFlankingSnpIDs(dragSelectRectangle);

        }
    });
    final MenuItem scmItem2 = new MenuItem("Write Selected Region to File");
    scmItem2.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            Platform.runLater(new Runnable() {
                @Override
                public void run() {
                    /* get coordinates of selection and report back
                     * write SNPs in region to file
                     */
                    writeRegionToFile(dragSelectRectangle);
                }
            });
        }
    });
    final MenuItem scmItem3 = new MenuItem("Add To Saved Regions");
    scmItem3.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            /* get coordinates of selection and report back
             * write SNPs in region to file
             */
            saveSelection();
        }
    });
    final MenuItem scmItem4 = new MenuItem("Show/Hide Saved Regions");
    scmItem4.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            /* get coordinates of selection and report back
             * write SNPs in region to file
             */
            hideSavedRegionsMenu.selectedProperty().setValue(!hideSavedRegionsMenu.isSelected());
            hideSavedRegionsMenu.fire();
        }
    });
    final MenuItem scmItem5 = new MenuItem("Zoom Region");
    scmItem5.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            Platform.runLater(new Runnable() {
                @Override
                public void run() {
                    /* get coordinates of selection and report back
                     * write SNPs in region to file
                     */
                    zoomRegion(dragSelectRectangle);
                }
            });
        }
    });
    final MenuItem scmItem6 = new MenuItem("Write Saved Regions to File");
    scmItem6.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            Platform.runLater(new Runnable() {
                @Override
                public void run() {
                    /* get coordinates of selection and report back
                     * write SNPs in region to file
                     */
                    writeSavedRegionsToFile();
                }
            });
        }
    });

    scm.getItems().add(scmItem1);
    scm.getItems().add(scmItem2);
    scm.getItems().add(scmItem3);
    scm.getItems().add(scmItem4);
    scm.getItems().add(scmItem5);
    scm.getItems().add(scmItem6);
    //overlayPane context menu
    ocm = new ContextMenu();
    final MenuItem ocmItem1 = new MenuItem("Save Image to File");
    ocmItem1.setOnAction(new EventHandler<ActionEvent>() {
        @Override
        public void handle(ActionEvent e) {
            Platform.runLater(new Runnable() {
                @Override
                public void run() {
                    drawPaneToPng();
                }
            });
        }
    });

    ocm.getItems().add(ocmItem1);
    ocm.getItems().add(scmItem4);
    ocm.getItems().add(scmItem6);

    //color selections
    colorComponantSelector.getItems().clear();
    colorComponantSelector.getItems().add("AA");
    colorComponantSelector.getItems().add("BB");
    colorComponantSelector.getItems().add("AB");
    colorComponantSelector.getItems().add("Selection Outline");
    colorComponantSelector.getItems().add("Selection Fill");
    colorComponantSelector.getItems().add("Saved Region Outline");
    colorComponantSelector.getItems().add("Saved Region Fill");
    colorComponantSelector.getSelectionModel().selectFirst();
    colorPicker.setValue(colorComponants[0]);
    colorComponantSelector.getSelectionModel().selectedIndexProperty()
            .addListener(new ChangeListener<Number>() {
                @Override
                public void changed(ObservableValue ov, Number value, Number new_value) {
                    colorPicker.setValue(colorComp.get(new_value.intValue()));
                    colorPicker.fireEvent(new ActionEvent());
                }
            });
    colorPicker.setOnAction(new EventHandler() {
        @Override
        public void handle(Event t) {
            if (!colorComp.get(colorComponantSelector.getSelectionModel().getSelectedIndex())
                    .equals(colorPicker.getValue())) {
                colorComp.set(colorComponantSelector.getSelectionModel().getSelectedIndex(),
                        colorPicker.getValue());
                saveProject();
                //colorComponants[colorComponantSelector.getSelectionModel().getSelectedIndex()] = colorPicker.getValue();
                if (colorComponantSelector.getSelectionModel().getSelectedIndex() == Colors.fill.value) {
                    dragSelectRectangle.setFill(colorPicker.getValue());
                } else if (colorComponantSelector.getSelectionModel().getSelectedIndex() == Colors.line.value) {
                    dragSelectRectangle.setStroke(colorPicker.getValue());
                } else if (colorComponantSelector.getSelectionModel()
                        .getSelectedIndex() == Colors.saveLine.value) {
                    for (Rectangle r : savedRegionsDisplay) {
                        r.setStroke(colorPicker.getValue());
                    }
                } else if (colorComponantSelector.getSelectionModel()
                        .getSelectedIndex() == Colors.saveFill.value) {
                    for (Rectangle r : savedRegionsDisplay) {
                        r.setFill(colorPicker.getValue());
                    }
                } else {
                    removeSavedChromosomeImages();
                    if (redrawCheckBox.isSelected()) {
                        refreshView(null, true);
                    }
                }
            }
        }
    });

    /*perform appropriate action when user selects a chromosome
     * from the chromosome choice box
     */
    chromosomeSelector.getSelectionModel().selectedIndexProperty().addListener(new ChangeListener<Number>() {
        @Override
        public void changed(ObservableValue ov, Number value, Number new_value) {
            chromosomeBoxList = chromosomeSelector.getItems().toArray();

            if (new_value.intValue() > -1) {
                chromosomeSelected((String) chromosomeBoxList[new_value.intValue()]);
            }
        }
    });

    chromosomeSelector.addEventFilter(KeyEvent.ANY, new EventHandler<KeyEvent>() {
        @Override
        public void handle(KeyEvent ke) {
            if (ke.getCode() == KeyCode.UP) {
                ke.consume();
                chromosomeSelector.show();
            }
        }
    });

    selectionOverlayPane.heightProperty().addListener(new ChangeListener<Number>() {
        @Override
        public void changed(ObservableValue<? extends Number> observableValue, Number oldSceneWidth,
                Number newSceneWidth) {
            windowResized(new ActionEvent());

        }
    });

    selectionOverlayPane.widthProperty().addListener(new ChangeListener<Number>() {
        @Override
        public void changed(ObservableValue<? extends Number> observableValue, Number oldSceneWidth,
                Number newSceneWidth) {
            windowResized(new ActionEvent());
        }
    });

    /*upon addition of a new affected file adjust components accordingly
     * i.e. ensure appropriate chromosomes are in the choice box
     * adjust the split panes to fit all files and redisplay
     */

    affObserve.addListener(new ListChangeListener() {
        @Override
        public void onChanged(ListChangeListener.Change change) {
            change.next();/*from the javadoc 
                          * 'Go to the next change. In initial state is invalid a require 
                          * a call to next() before calling other methods. The first 
                          * next() call will make this object represent the first change.
                          */
            if (change.getRemovedSize() > 0) {
                List<SnpFile> both = new ArrayList<>(unFiles);
                both.addAll(affFiles);
                recheckChromosomeSelector(both);//need to check all files again, not just affFiles
            } else if (change.getAddedSize() > 0) {
                addToChromosomeSelector(affFiles);
            }
        }
    });

    /*as above 
     * but for unaffected files
     */
    unObserve.addListener(new ListChangeListener() {
        @Override
        public void onChanged(ListChangeListener.Change change) {
            change.next();
            if (change.getRemovedSize() > 0) {
                List<SnpFile> both = new ArrayList<>(unFiles);
                both.addAll(affFiles);
                recheckChromosomeSelector(both);//need to check all files again, not just unFiles
            } else if (change.getAddedSize() > 0) {
                addToChromosomeSelector(unFiles);
            }

        }
    });

    selectionOverlayPane.addEventHandler(MouseEvent.MOUSE_MOVED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            if (!genomeVersion.equals("") && chromosomeSelector.getSelectionModel().getSelectedIndex() > -1) {
                try {
                    ChromosomeLength chromLength = new ChromosomeLength(genomeVersion);
                    String currentChrom = (String) chromosomeBoxList[chromosomeSelector.getSelectionModel()
                            .getSelectedIndex()];
                    double coordinate = chromLength.getLength(currentChrom) / chromSplitPane.getWidth()
                            * e.getX();
                    positionIndicator.setText(nf.format(coordinate));

                } catch (Exception ex) {
                    positionIndicator.setText("Build Error!");
                }

            }
        }
    });
    /*handle mouse dragging and effect on dragSelectRectangle
     * 
     */
    dragSelectRectangle.widthProperty().bind(dragSelectRectX.subtract(dragSelectRectInitX));
    dragSelectRectangle.heightProperty().bind(selectionOverlayPane.heightProperty());
    //dragSelectRectangle.strokeProperty().set(colorComponants[Colors.line.value]);
    dragSelectRectangle.setStrokeWidth(4.0);

    //dragSelectRectangle.setBlendMode(BlendMode.SCREEN);
    dragSelectRectangle.setOpacity(0.45);
    dragSelectRectangle.setVisible(false);
    selectionOverlayPane.getChildren().add(dragSelectRectangle);

    selectionOverlayPane.addEventHandler(MouseEvent.MOUSE_PRESSED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            if (scm.isShowing()) {
                scm.hide();
            }
            if (!e.isPrimaryButtonDown()) {
                if (e.isSecondaryButtonDown()) {
                    //check we're not overlapping selection
                    if (e.getX() >= dragSelectRectangle.getX()
                            && e.getX() <= (dragSelectRectangle.getX() + dragSelectRectangle.getWidth())) {
                        return;
                    }
                    //check we're not overlapping saved regions
                    for (Rectangle r : savedRegionsDisplay) {
                        if (r.isVisible() && e.getX() >= r.getX() && e.getX() <= r.getX() + r.getWidth()) {
                            return;
                        }
                    }
                    if (chromosomeSelector.getSelectionModel().isEmpty()) {
                        ocmItem1.setDisable(true);
                    } else {
                        ocmItem1.setDisable(false);
                    }
                    ocm.show(selectionOverlayPane, e.getScreenX(), e.getScreenY());

                    return;
                }
            }
            if (ocm.isShowing()) {
                ocm.hide();
            }

            dragSelectRectangle.strokeProperty().set(colorComp.get(Colors.line.value));
            dragSelectRectangle.fillProperty().set(colorComp.get(Colors.fill.value));
            dragSelectRectX.set(0);
            dragSelectRectangle.setVisible(true);
            dragSelectRectangle.setX(e.getX());
            dragSelectRectangle.setY(0);
            dragSelectRectInitX.set(e.getX());
            anchorInitX.set(e.getX());

        }
    });
    selectionOverlayPane.addEventHandler(MouseEvent.MOUSE_DRAGGED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            if (!e.isPrimaryButtonDown()) {
                return;
            }
            dragSelectRectangle.setVisible(true);
            if (e.getX() > anchorInitX.doubleValue()) {//dragging to the right
                if (e.getX() <= selectionOverlayPane.getLayoutX() + selectionOverlayPane.getWidth()) {
                    //mouse is before the edge of the pane
                    dragSelectRectInitX.set(anchorInitX.doubleValue());
                    dragSelectRectX.set(e.getX());
                } else {
                    //mouse is over the edge
                    dragSelectRectX.set(selectionOverlayPane.getWidth());
                }
            } else {
                if (e.getX() > selectionOverlayPane.getLayoutX()) {
                    dragSelectRectInitX.set(e.getX());
                    dragSelectRectangle.setX(e.getX());
                    dragSelectRectX.set(anchorInitX.doubleValue());
                } else {
                    dragSelectRectInitX.set(0);
                    dragSelectRectangle.setX(0);
                    /* the two lines below are just to trigger 
                    * dragSelectRectangle.widthProperty listener 
                    * so that start coordinate changes to 1
                    */
                    dragSelectRectX.set(anchorInitX.doubleValue() + 1);
                    dragSelectRectX.set(anchorInitX.doubleValue() + 1);

                }
            }
        }
    });

    selectionOverlayPane.addEventHandler(MouseEvent.MOUSE_RELEASED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            //dragSelectRectX.set(e.getX());
            if (!e.isPrimaryButtonDown()) {
                return;
            }
            dragSelectRectangle.setVisible(true);
            if (dragSelectRectangle.getWidth() == 0) {
                clearDragSelectRectangle();
            }
        }
    });

    dragSelectRectangle.widthProperty().addListener(new ChangeListener() {
        @Override
        public void changed(ObservableValue observableValue, Object oldValue, Object newRectWidth) {
            if (!genomeVersion.equals("") && chromosomeSelector.getSelectionModel().getSelectedIndex() > -1
                    && dragSelectRectangle.getWidth() > 0) {
                try {
                    ChromosomeLength chromLength = new ChromosomeLength(genomeVersion);
                    String currentChrom = (String) chromosomeBoxList[chromosomeSelector.getSelectionModel()
                            .getSelectedIndex()];
                    double startCoordinate = chromLength.getLength(currentChrom)
                            / selectionOverlayPane.getWidth() * dragSelectRectangle.getX();
                    double selectionWidth = chromLength.getLength(currentChrom)
                            / selectionOverlayPane.getWidth() * dragSelectRectangle.getWidth();
                    if (dragSelectRectangle.getX() == 0) {
                        startCoordinate = 1;
                    }
                    selectionIndicator.setText("chr" + currentChrom + ":" + nf.format(startCoordinate) + "-"
                            + nf.format(startCoordinate + selectionWidth));
                } catch (Exception ex) {
                    selectionIndicator.setText("Build Error!");
                }
            } else {
                selectionIndicator.setText("");
            }

        }
    });

    dragSelectRectangle.addEventHandler(MouseEvent.MOUSE_CLICKED, new EventHandler<MouseEvent>() {
        @Override
        public void handle(MouseEvent e) {
            if (e.getButton() == MouseButton.SECONDARY) {
                if (chromosomeSelector.getSelectionModel().isEmpty()) {
                    scmItem1.setDisable(true);
                    scmItem2.setDisable(true);
                } else {
                    scmItem1.setDisable(false);
                    scmItem2.setDisable(false);
                }
                if (ocm.isShowing()) {
                    ocm.hide();
                }

                scm.show(selectionOverlayPane, e.getScreenX(), e.getScreenY());
            }
        }
    });

}