Use GridSizer control : GridSizer « wxPython « Python Tutorial

1. Python Tutorial
2. wxPython
3. GridSizer

import wx

class BlockWindow(wx.Panel):
    def __init__(self, parent, ID=-1, label="", pos=wx.DefaultPosition, size=(100, 25)):
        wx.Panel.__init__(self, parent, ID, pos, size, wx.RAISED_BORDER, label)
        self.label = label
        self.SetMinSize(size)
        self.Bind(wx.EVT_PAINT, self.OnPaint)

    def OnPaint(self, evt):
        sz = self.GetClientSize()
        dc = wx.PaintDC(self)
        w,h = dc.GetTextExtent(self.label)
        dc.SetFont(self.GetFont())
        dc.DrawText(self.label, (sz.width-w)/2, (sz.height-h)/2)
        
labels = "1 2 3 4 5 6 7 8 9 0".split()

class GridSizerFrame(wx.Frame):
    def __init__(self):
        wx.Frame.__init__(self, None, -1, "Grid Sizer")
        sizer = wx.GridSizer(rows=3, cols=3, hgap=5, vgap=5)
        for label in labels:
            bw = BlockWindow(self, label=label)
            sizer.Add(bw, 0, 0)
        self.SetSizer(sizer)
        self.Fit()

app = wx.PySimpleApp()
GridSizerFrame().Show()
app.MainLoop()

19.18.GridSizer
	19.18.1.	Use GridSizer control