Choose a file from FileDialog : FileDialog « wxPython « Python Tutorial

1. Python Tutorial
2. wxPython
3. FileDialog

import wx
import os


app = wx.PySimpleApp()
wildcard = "Python source (*.py)|*.py|" 
        "Compiled Python (*.pyc)|*.pyc|" \
        "All files (*.*)|*.*"
dialog = wx.FileDialog(None, "Choose a file", os.getcwd(), "", wildcard, wx.OPEN)
if dialog.ShowModal() == wx.ID_OK:
    print dialog.GetPath() 

dialog.Destroy()