is() can be used inside an event handler.
<html>
<head>
<script type="text/javascript" src="js/jquery-1.3.2.js"></script>
<script type="text/javascript">
$(document).ready(function(){
$("div").one('click', function () {
if ($(this).is(":first-child")) {
$("p").text(":first-child");
} else if ($(this).is(".blue,.red")) {
$("p").text("It's a blue or red div.");
} else if ($(this).is(":contains('asdf')")) {
$("p").text("It's asdf!");
} else {
$("p").html("It's nothing <em>special</em>.");
}
});
});
</script>
<style>
div.middle { color: red; }
</style>
</head>
<body>
<body>
<div>asdf</div>
<div class="blue">asdf</div>
<div class="red">asdf</div>
<div><span>asdf</span>asdf</div>
<div class="blue">asdf</div>
<p>asdf</p>
</body>
</html>
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