Remove class
<html> <head> <script type="text/javascript"> var djConfig = { baseScriptUri : "js/dojo/", parseOnLoad : true }; </script> <script type="text/javascript" src="js/dojo/dojo/dojo.js"></script> <style> .oldClass { background-color : blue; } </style> <script> dojo.require("dojox.fx.style"); function testIt() { dojox.fx.removeClass({cssClass:"oldClass", node:"div1"}).play(); } </script> </head> <body onload=testIt()> <div id="div1" class="oldClass">Text</div> </body> </html>