p:first-letter font-size: 200%;
<html>
<head>
<title></title>
<style type="text/css">
* {
font-family: verdana, arial, sans-serif;
}
h1 {
font-size: 120%;
}
#navigation {
border: 1px solid black;
padding: 40px;
}
li a {
text-decoration: none;
}
p {
font-size: 90%;
}
.warning {
font-weight: bold;
}
p:first-letter {
font-size: 200%;
font-weight: bold;
}
</style>
</head>
<body>
<h1>Title of Page</h1>
<p>This is a sample paragraph with a <a href="http://csscookbook.com" class="warning">link</a>.
Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore
magna <em class="warning">aliquam erat volutpat</em>. Ut wisi enim ad minim veniam, quis nostrud exerci
tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo consequat.</p>
<ul id="navigation">
<li class="warning"><a href="http://csscookbook.com">Apples</a></li>
<li><a href="http://csscookbook.com">Bananas</a></li>
<li><a href="http://csscookbook.com">Cherries</a></li>
</ul>
</body>
</html>
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