Use VDividedBox to hold List
<?xml version="1.0" encoding="utf-8"?>
<mx:Application xmlns:mx="http://www.adobe.com/2006/mxml">
<mx:Panel layout="horizontal" width="100%" height="100%" title="this is a test">
<mx:VDividedBox direction="vertical" width="200" height="100%">
<mx:List width="100%" height="200">
</mx:List>
<mx:List width="100%">
</mx:List>
</mx:VDividedBox>
<mx:Canvas width="100%" height="100%">
<mx:Button bottom="10" right="10" label="Save"/>
</mx:Canvas>
</mx:Panel>
</mx:Application>
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